Zhou Qian, Rao Qiuchen, Li Haidong, Zhang Ming, Zhao Xiuchao, Shi Lei, Ye Chaohui, Zhou Xin
Key Laboratory of Magnetic Resonance in Biological Systems, State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, National Center for Magnetic Resonance in Wuhan, Wuhan Institute of Physics and Mathematics, Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences-Wuhan National Laboratory for Optoelectronics, Wuhan, 430071, China.
University of Chinese Academy of Sciences, Beijing, 100049, China.
Magn Reson Lett. 2021 Aug;1(1):2-10. doi: 10.1016/j.mrl.2021.100009. Epub 2021 Aug 8.
The ongoing pandemic of coronavirus disease 2019 (COVID-19) has been a great burden for the healthcare system in many countries because of its high transmissibility, severity, and fatality. Chest radiography and computed tomography (CT) play a vital role in the diagnosis, detection of complications, and prognostication of COVID-19. Additionally, magnetic resonance imaging (MRI), especially multi-nuclei MRI, is another important imaging technique for disease diagnosis because of its good soft tissue contrast and the ability to conduct structural and functional imaging, which has also been used to evaluate COVID-19-related organ injuries in previous studies. Herein, we briefly reviewed the recent research on multi-nuclei MRI for evaluating injuries caused by COVID-19 and the clinical H MRI techniques and their applications for assessing injuries in lungs, brain, and heart. Moreover, the emerging hyperpolarized Xe gas MRI and its applications in the evaluation of pulmonary structures and functional abnormalities caused by COVID-19 were also reviewed.
2019年冠状病毒病(COVID-19)的持续大流行给许多国家的医疗系统带来了巨大负担,因为它具有高传播性、严重性和致死性。胸部X线摄影和计算机断层扫描(CT)在COVID-19的诊断、并发症检测和预后评估中起着至关重要的作用。此外,磁共振成像(MRI),尤其是多核MRI,因其良好的软组织对比度以及进行结构和功能成像的能力,是疾病诊断的另一项重要成像技术,在先前的研究中也已用于评估与COVID-19相关的器官损伤。在此,我们简要回顾了多核MRI用于评估COVID-19所致损伤的最新研究以及临床MRI技术及其在评估肺、脑和心脏损伤中的应用。此外,还综述了新兴的超极化氙气MRI及其在评估COVID-19引起的肺部结构和功能异常中的应用。