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Enigma of COVID-19: is "multisystem inflammatory syndrome in adults" (MIS-A) predictable?新冠病毒之谜:成人多系统炎症综合征(MIS-A)是否可预测?
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2
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BMJ Case Rep. 2021 Oct 1;14(10):e243114. doi: 10.1136/bcr-2021-243114.
3
Clinical Characteristics of Multisystem Inflammatory Syndrome in Adults: A Systematic Review.成人多系统炎症综合征的临床特征:系统评价。
JAMA Netw Open. 2021 Sep 1;4(9):e2126456. doi: 10.1001/jamanetworkopen.2021.26456.
4
Host Genetics and Antiviral Immune Responses in Adult Patients With Multisystem Inflammatory Syndrome.宿主遗传学与成人多系统炎症综合征患者的抗病毒免疫反应。
Front Immunol. 2021 Aug 31;12:718744. doi: 10.3389/fimmu.2021.718744. eCollection 2021.
5
Racial and Ethnic Disparities in Multisystem Inflammatory Syndrome in Children in the United States, March 2020 to February 2021.美国 2020 年 3 月至 2021 年 2 月儿童多系统炎症综合征中的种族和民族差异。
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Multisystem inflammatory syndrome in adults: A rare sequela of SARS-CoV-2 infection.成人多系统炎症综合征:一种罕见的 SARS-CoV-2 感染后遗症。
Int J Infect Dis. 2021 Jul;108:209-211. doi: 10.1016/j.ijid.2021.05.050. Epub 2021 May 24.
7
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一名免疫抑制成人的多系统炎症综合征病例。

A Case of Multisystem Inflammatory Syndrome in an Immunosuppressed Adult.

作者信息

Razzak Abrahim N, Janardan Abhishek, Shah Ipsit, Jha Pinky, Abdelgadir Yasir

机构信息

School of Medicine, Medical College of Wisconsin, Milwaukee, USA.

Internal Medicine, Medical College of Wisconsin, Milwaukee, USA.

出版信息

Cureus. 2022 Jun 3;14(6):e25635. doi: 10.7759/cureus.25635. eCollection 2022 Jun.

DOI:10.7759/cureus.25635
PMID:35673620
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9165724/
Abstract

Multisystem inflammatory syndrome in an adult (MIS-A) is a rare immunological complication that gained prominence after the coronavirus disease 2019 pandemic. Patients with MIS-A often clinically present with non-specific generalized symptoms, such as fever, myalgia, or fatigue, making the diagnosis difficult. In this article, we present an unusual case of MIS-A in a 50-year-old male that raises the question of whether the immune system's dysregulation will demonstrate differing criteria of signs and symptoms for a patient on sustained immunosuppression as opposed to the non-immunosuppressed population.

摘要

成人多系统炎症综合征(MIS-A)是一种罕见的免疫并发症,在2019年冠状病毒病大流行后受到关注。MIS-A患者临床上常表现为非特异性全身症状,如发热、肌痛或疲劳,这使得诊断困难。在本文中,我们介绍了一例50岁男性的罕见MIS-A病例,该病例引发了一个问题:与未接受免疫抑制的人群相比,持续接受免疫抑制治疗的患者免疫系统失调是否会表现出不同的体征和症状标准。