从 的根部分离得到两种新的异黄酮。
Two new isoflavones from the roots of .
机构信息
State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang 550014, China.
Guizhou Bailing Enterprise Group Pharmaceutical Co., Ltd, Anshun 561000, China.
出版信息
J Asian Nat Prod Res. 2023 Feb;25(2):163-170. doi: 10.1080/10286020.2022.2077200. Epub 2022 Jun 8.
Two new isoflavones ( and ), as well as eight known ones were isolated from the roots of Gagnep. Compound represents an unprecedented polymerization pattern constructed by isoflavone and cytisine. Their structures were elucidated by comprehensive spectroscopic data analysis, combined with ECD calculations. Compound displayed significant anti-tobacco mosaic virus (TMV) activity compared with the positive control ningnanmycin. Moreover, compound exhibited potent -glucosidase inhibitory activity with IC value of 47.4 mg/L.
从 Gagnep 的根部分离得到两种新的异黄酮（和）以及八种已知的异黄酮。化合物代表了由异黄酮和野靛碱构建的前所未有的聚合模式。通过全面的光谱数据分析，并结合 ECD 计算，确定了它们的结构。与阳性对照宁南霉素相比，化合物表现出显著的抗烟草花叶病毒（TMV）活性。此外，化合物对 -葡萄糖苷酶表现出很强的抑制活性，IC 值为 47.4 mg/L。
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