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阿尔茨海默病型痴呆中的发音复述

Articulatory rehearsal in Alzheimer type dementia.

作者信息

Morris R G

出版信息

Brain Lang. 1987 Mar;30(2):351-62. doi: 10.1016/0093-934x(87)90108-8.

DOI:10.1016/0093-934x(87)90108-8
PMID:3567554
Abstract

This study investigated the relationship between articulation rate and memory span in a sample of 21 patients with early Alzheimer type dementia (AD), comparing their performance with 21 matched controls. Memory span was measured using auditorily and visually presented digits. The AD patients were moderately impaired in both conditions. Articulation rate was measured either by requiring subjects to read lists of random digits or repeatedly count from 1 to 10. The AD patients were able to read the digits as fast as the controls but were slower in the counting task. The measures of memory span and articulation rate correlated significantly for the controls but not for the AD patients, indicating that the normal association between articulation and memory span is disrupted. These results are discussed in relation to previous results and suggest that articulatory rehearsal processes in primary memory are unimpaired at the early stages of AD.

摘要

本研究调查了21例早期阿尔茨海默型痴呆(AD)患者样本中言语清晰度速率与记忆广度之间的关系,并将他们的表现与21名匹配的对照组进行比较。记忆广度通过听觉和视觉呈现数字来测量。AD患者在两种情况下均有中度受损。言语清晰度速率通过要求受试者阅读随机数字列表或从1到10反复计数来测量。AD患者阅读数字的速度与对照组一样快,但在计数任务中较慢。对照组的记忆广度和言语清晰度速率测量值显著相关,而AD患者则不然,这表明言语清晰度与记忆广度之间的正常关联被破坏。这些结果与先前的结果相关进行了讨论,并表明初级记忆中的言语复述过程在AD早期并未受损。

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