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阿尔茨海默病型痴呆中的初级记忆和工作记忆功能

Primary and working memory functioning in Alzheimer-type dementia.

作者信息

Morris R G, Baddeley A D

机构信息

University of Toronto, Canada.

出版信息

J Clin Exp Neuropsychol. 1988 Mar;10(2):279-96. doi: 10.1080/01688638808408242.

DOI:10.1080/01688638808408242
PMID:3280591
Abstract

This paper reviews recent neuropsychological studies of primary-memory functioning in early Alzheimer-type dementia (AD) with specific reference to recent research on working memory. The deficits in primary memory follow a fairly distinct pattern with a comparatively unimpaired recency effect in free recall, a moderate impairment in memory span, and a more substantial impairment in short-term retention following distraction. The nature of these deficits is considered in relation to the Working Memory Model (Baddeley & Hitch, 1974). It is suggested that the Articulatory Loop System is functioning normally but that there is an impairment in the control processes of working memory.

摘要

本文回顾了近期对早期阿尔茨海默病型痴呆(AD)患者初级记忆功能的神经心理学研究,特别提及了近期关于工作记忆的研究。初级记忆缺陷呈现出一种相当独特的模式,在自由回忆中近期效应相对未受损害,记忆广度有中度损害,而在分心后的短期保持方面有更严重的损害。这些缺陷的本质与工作记忆模型(Baddeley & Hitch,1974)相关进行了探讨。研究表明,言语环路系统功能正常,但工作记忆的控制过程存在损害。

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