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大鼠终纹床核:出生后早期由性腺类固醇控制的区域性别差异。

The bed nucleus of the stria terminalis in the rat: regional sex differences controlled by gonadal steroids early after birth.

作者信息

del Abril A, Segovia S, Guillamón A

出版信息

Brain Res. 1987 Apr;429(2):295-300. doi: 10.1016/0165-3806(87)90110-6.

DOI:10.1016/0165-3806(87)90110-6
PMID:3567668
Abstract

The effects of postnatal (on day 1 (D1) after birth) male orchidectomy and female androgenization on the bed nucleus of the stria terminalis (BNST) were studied. The volume of the medial posterior region of the BNST was greater in the control males than in the control females. Postnatal treatment reversed these differences. Sex differences were also found in the medial anterior region of the BNST where female rats always showed a greater volume than did the males. Female androgenization on D1 did not affect the volume of the BNST medial anterior region. However, D1 male orchidectomy did increase significantly the volume of this region. No sex differences were found in lateral, ventral or intermediate BNST divisions.

摘要

研究了出生后(出生后第1天,即D1)雄性去势和雌性雄激素化对终纹床核(BNST)的影响。对照组雄性BNST内侧后区的体积大于对照组雌性。出生后的处理逆转了这些差异。在BNST内侧前区也发现了性别差异,雌性大鼠的该区域体积总是大于雄性。出生后第1天的雌性雄激素化并未影响BNST内侧前区的体积。然而,出生后第1天的雄性去势确实显著增加了该区域的体积。在BNST的外侧、腹侧或中间区未发现性别差异。

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