• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

同步性结肠癌和乳腺癌:一例多原发性肿瘤病例报告

Synchronous Colon and Breast Cancers: A Case Report of Multiple Primary Tumors.

作者信息

Bin Saleem Moneera Y, Albandar Mahdi H, Alfaifi Jaber A

机构信息

General Surgery, King Abdullah Bin Abdulaziz University Hospital, Princess Nourah Bint Abdulrahman University, Riyadh, SAU.

Department of Surgery, King Saud Medical City, Riyadh, SAU.

出版信息

Cureus. 2022 May 7;14(5):e24798. doi: 10.7759/cureus.24798. eCollection 2022 May.

DOI:10.7759/cureus.24798
PMID:35676989
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9169435/
Abstract

Multiple primary malignant tumors (MPMNs) are not rare entities. We report a case of a 50-year-old female who presented with left upper quadrant abdominal pain and GI bleeding. Initial assessment with CT scan revealed a mass originating from the descending colon. Colonoscopy was performed and a fungating partially obstructed mass at the left splenic flexure was detected. Histopathological examination of biopsy was consistent with mucinous adenocarcinoma. The staging CT scan of the chest and pelvis, followed by a mammogram reported a Synchronous breast mass. Core needle biopsy detected an invasive ducal carcinoma. In the multidisciplinary meeting, it was decided to perform the colon procedure first, followed by adjuvant chemotherapy, and then the breast procedure. The patient had an uneventful recovery after both procedures and was sent to the medical oncology department to continue with the treatment.

摘要

多原发性恶性肿瘤(MPMNs)并非罕见病例。我们报告一例50岁女性,她因左上腹疼痛和胃肠道出血就诊。CT扫描初步评估发现一个起源于降结肠的肿块。进行了结肠镜检查,在脾曲处发现一个呈蕈状、部分阻塞的肿块。活检的组织病理学检查结果与黏液腺癌相符。胸部和骨盆的分期CT扫描以及随后的乳房X光检查报告发现一个同步性乳房肿块。粗针活检检测到浸润性导管癌。在多学科会议上,决定先进行结肠手术,然后进行辅助化疗,接着进行乳房手术。两次手术后患者恢复顺利,并被送往医学肿瘤科继续治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5cb2/9169435/8831886441d1/cureus-0014-00000024798-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5cb2/9169435/26da2850d2be/cureus-0014-00000024798-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5cb2/9169435/fa854899b7f4/cureus-0014-00000024798-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5cb2/9169435/8831886441d1/cureus-0014-00000024798-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5cb2/9169435/26da2850d2be/cureus-0014-00000024798-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5cb2/9169435/fa854899b7f4/cureus-0014-00000024798-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5cb2/9169435/8831886441d1/cureus-0014-00000024798-i03.jpg

相似文献

1
Synchronous Colon and Breast Cancers: A Case Report of Multiple Primary Tumors.同步性结肠癌和乳腺癌:一例多原发性肿瘤病例报告
Cureus. 2022 May 7;14(5):e24798. doi: 10.7759/cureus.24798. eCollection 2022 May.
2
Synchronous Occurrence of Primary Breast Carcinoma and Primary Colon Adenocarcinoma.原发性乳腺癌与原发性结肠腺癌的同步发生
Case Rep Surg. 2017;2017:7048149. doi: 10.1155/2017/7048149. Epub 2017 Oct 25.
3
Synchronous breast and colon cancer: the importance of multidisciplinary team cancer meetings.同步性乳腺癌和结肠癌:多学科团队癌症会议的重要性。
BMJ Case Rep. 2019 Dec 4;12(12):e232680. doi: 10.1136/bcr-2019-232680.
4
Synchronous Adenocarcinoma of the Colon and Rectal Carcinoid.结肠同步腺癌与直肠类癌
Case Rep Gastroenterol. 2016 Oct 18;10(3):600-604. doi: 10.1159/000450677. eCollection 2016 Sep-Dec.
5
Synchronous occurrence of breast cancer and refractory diffuse large B-cell abdominal lymphoma: Management and review of the literature.乳腺癌与难治性弥漫性大B细胞腹部淋巴瘤的同步发生:治疗及文献综述
Intractable Rare Dis Res. 2021 May;10(2):131-135. doi: 10.5582/irdr.2021.01017.
6
Bilateral synchronous breast carcinomas followed by a metastasis to the gallbladder: a case report.双侧同步性乳腺癌继发胆囊转移:一例报告
World J Surg Oncol. 2007 Sep 11;5:101. doi: 10.1186/1477-7819-5-101.
7
Synchronous gist, colon and breast adenocarcinoma with double colonic polyp metastases.同时性原发性肿瘤,结肠和乳腺腺癌伴双发性结肠息肉转移。
Int J Surg Case Rep. 2014;5(8):523-6. doi: 10.1016/j.ijscr.2014.04.020. Epub 2014 Jun 4.
8
Synchronous occurrence of primary breast cancer and renal cell carcinoma: A case report and literature review.原发性乳腺癌与肾细胞癌的同步发生:一例报告及文献综述
Int J Surg Case Rep. 2024 Jun;119:109778. doi: 10.1016/j.ijscr.2024.109778. Epub 2024 May 18.
9
Metastatic Mixed Adeno-Neuroendocrine Carcinoma of the Colon to the Liver with Multiple Peritoneal Deposits: A Case Report.结直肠转移性混合性腺神经内分泌癌肝转移伴多发腹膜转移:1 例报告
Am J Case Rep. 2021 Apr 15;22:e929099. doi: 10.12659/AJCR.929099.
10
A malignant mass in the breast is not always breast cancer.乳房中的恶性肿块并不总是乳腺癌。
Case Rep Oncol. 2011 Sep;4(3):521-5. doi: 10.1159/000334079. Epub 2011 Oct 21.

引用本文的文献

1
Breast cancer as the first primary malignancy: clinical pathological characteristics of common cancer combinations.乳腺癌作为首发原发性恶性肿瘤:常见癌症组合的临床病理特征
Discov Oncol. 2025 Aug 23;16(1):1599. doi: 10.1007/s12672-025-03427-w.
2
Synchronous Primary Malignancies: Incidental Detection of Ascending Colon Adenocarcinoma During Staging of Invasive Ductal Carcinoma of the Breast.同步原发性恶性肿瘤:在乳腺癌浸润性导管癌分期过程中偶然发现升结肠癌。
Case Rep Oncol Med. 2025 Mar 11;2025:7164628. doi: 10.1155/crom/7164628. eCollection 2025.
3
Synchronous Breast and Colorectal Malignant Tumors-A Systematic Review.

本文引用的文献

1
Breast Cancer and Multiple Primary Malignant Tumors: Case Report and Review of the Literature.乳腺癌与多原发恶性肿瘤:病例报告及文献复习。
In Vivo. 2019 Jul-Aug;33(4):1313-1324. doi: 10.21873/invivo.11605.
2
Multiple Primary Malignant Tumors - A Clinical Analysis of 15,321 Patients with Malignancies at a Single Center in China.多原发性恶性肿瘤——中国某单中心15321例恶性肿瘤患者的临床分析
J Cancer. 2018 Jul 16;9(16):2795-2801. doi: 10.7150/jca.25482. eCollection 2018.
3
Metachronous and Synchronous Occurrence of 5 Primary Malignancies in a Female Patient between 1997 and 2013: A Case Report with Germline and Somatic Genetic Analysis.
同步性乳腺与结直肠癌恶性肿瘤——一项系统综述
Life (Basel). 2024 Aug 13;14(8):1008. doi: 10.3390/life14081008.
1997年至2013年间一名女性患者5种原发性恶性肿瘤的异时性和同时性发生:一项伴有胚系和体细胞基因分析的病例报告
Case Rep Oncol. 2017 Nov 16;10(3):1006-1012. doi: 10.1159/000484403. eCollection 2017 Sep-Dec.
4
The risk of second cancers after diagnosis of primary thyroid cancer is elevated in thyroid microcarcinomas.甲状腺微小癌患者在确诊原发性甲状腺癌后发生第二原发癌的风险增加。
Thyroid. 2013 May;23(5):575-82. doi: 10.1089/thy.2011.0406. Epub 2013 Apr 18.
5
Germline SDHx variants modify breast and thyroid cancer risks in Cowden and Cowden-like syndrome via FAD/NAD-dependant destabilization of p53.胚系 SDHx 变异通过 FAD/NAD 依赖性 p53 失稳改变 Cowden 及类 Cowden 综合征的乳腺癌和甲状腺癌风险。
Hum Mol Genet. 2012 Jan 15;21(2):300-10. doi: 10.1093/hmg/ddr459. Epub 2011 Oct 6.
6
Outcomes for patients who develop both breast and colorectal cancer.同时患有乳腺癌和结直肠癌患者的结局。
Ann Surg Oncol. 2012 Jan;19(1):242-8. doi: 10.1245/s10434-011-1843-8. Epub 2011 Jun 24.
7
Multiple primary cancers of the colon, rectum, and the thyroid gland.结肠、直肠和甲状腺的多原发性癌。
Saudi J Gastroenterol. 2008 Oct;14(4):202-5. doi: 10.4103/1319-3767.43277.
8
Thymoma and multiple malignancies: a case of five synchronous neoplasms and literature review.胸腺瘤与多种恶性肿瘤:一例同时存在五种肿瘤的病例及文献综述
Clin Med Res. 2003 Jul;1(3):227-32. doi: 10.3121/cmr.1.3.227.
9
An update on Lynch syndrome.林奇综合征的最新进展。
Curr Opin Oncol. 1998 Jul;10(4):349-56. doi: 10.1097/00001622-199807000-00012.
10
Chemical exposures, medical history, and risk of squamous and basal cell carcinoma of the skin.化学物质暴露、病史与皮肤鳞状细胞癌和基底细胞癌风险
Cancer Epidemiol Biomarkers Prev. 1996 Jun;5(6):419-24.