乙酰胆碱酯酶抑制剂在治疗电休克治疗后持续性谵妄中的作用
The Role of Acetylcholinesterase Inhibitors in the Treatment of Prolonged Postelectroconvulsive Therapy Delirium.
作者信息
Gutowski Brianna, Bomasang-Layno Emily
机构信息
Christiana Care Health System, 4755 Ogletown Stanton Rd, Newark, DE 19718, USA.
出版信息
Case Rep Psychiatry. 2022 May 30;2022:6966882. doi: 10.1155/2022/6966882. eCollection 2022.
Abstract
Electroconvulsive therapy (ECT) is an extremely effective treatment modality for severe depression but is often associated with transient or persistent cognitive impairment. ECT-induced cognitive impairment, however, can serve as a deterrent to completion of treatment. We present a case of a prolonged post-ECT delirium lasting approximately 3 weeks in which donepezil, an acetylcholinesterase inhibitor, was used and was successful in shortening the duration of post-ECT delirium.
摘要
电休克疗法（ECT）是治疗重度抑郁症的一种极其有效的治疗方式，但常常与短暂性或持续性认知障碍相关。然而，ECT引起的认知障碍可能会阻碍治疗的完成。我们报告一例ECT后谵妄持续约3周的病例，其中使用了乙酰胆碱酯酶抑制剂多奈哌齐，成功缩短了ECT后谵妄的持续时间。
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