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HIV 预防研究经验:男男性行为者和跨性别有色人种。

HIV Prevention Research Experiences Among Men Who Have Sex With Men and Transgender Persons of Color.

机构信息

Division of Infectious Diseases, Department of Medicine, Rutgers New Jersey Medical School, Newark, USA.

出版信息

J Racial Ethn Health Disparities. 2023 Aug;10(4):1542-1548. doi: 10.1007/s40615-022-01340-4. Epub 2022 Jun 9.

Abstract

PURPOSE

Black and Latinx MSM and transgender POC disproportionately experience new HIV diagnoses. Determining effective HIV prevention methods requires the inclusion of these communities in research and thorough post-trial experience evaluations. This study sought to evaluate the experiences of Black and Latinx MSM and transgender POC in HIV prevention research and identify facilitators and barriers to continued trials participation.

METHODS

A survey was developed in partnership with the community engagement team based on emerging themes during research participant check-ins with the team. The survey was built in REDCap and distributed to participants via text message. The survey assessed experiences with the research process time commitments, study responsibilities, compensation, experiences with Truvada®, characteristics of the research study team and site, barriers to continued study participation, willingness to participate in future studies, and overall satisfaction. All statistical analysis was completed in Stata.

RESULTS

Forty-four participants were enrolled in the study. Most participants (98%) were satisfied with their experiences in HIV prevention research. Job or school schedules were the most frequently cited barrier to study participation while Truvada® provision and adequate study visit compensation, length, number, and frequency were facilitators. Participants reported that research staff made them feel comfortable when talking about sexual behaviors, alcohol use, mental health, drug use, housing problems, violence in relationships, and legal problems.

CONCLUSIONS

Evaluating the experiences of key communities in HIV prevention research can help identify barriers and facilitators to clinical trials engagement and improve the design of future trials.

摘要

目的

黑人和拉丁裔男男性行为者和跨性别少数群体(POC)不成比例地经历新的 HIV 诊断。确定有效的 HIV 预防方法需要将这些群体纳入研究,并对试验后经验进行彻底评估。本研究旨在评估黑人和拉丁裔男男性行为者和跨性别 POC 在 HIV 预防研究中的经验,并确定继续参与试验的促进因素和障碍。

方法

一项调查是在社区参与团队的合作下开发的,该调查是基于团队与研究参与者定期交流中出现的主题。该调查是在 REDCap 中构建的,并通过短信分发给参与者。该调查评估了研究过程中的经验、时间承诺、研究责任、补偿、特鲁瓦达®的体验、研究团队和地点的特征、继续参与研究的障碍、参与未来研究的意愿以及总体满意度。所有统计分析均在 Stata 中完成。

结果

共有 44 名参与者入组本研究。大多数参与者(98%)对他们在 HIV 预防研究中的经验感到满意。工作或学校时间表是参与研究的最常见障碍,而特鲁瓦达®的提供以及充足的研究访问补偿、长度、数量和频率是促进因素。参与者报告说,研究人员在谈论性行为、饮酒、心理健康、药物使用、住房问题、关系中的暴力和法律问题时,让他们感到舒适。

结论

评估 HIV 预防研究中关键群体的经验可以帮助确定参与临床试验的障碍和促进因素,并改进未来试验的设计。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2bdc/10322760/d86ceed80039/40615_2022_1340_Fig1_HTML.jpg

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