Centre for Biostatistics, The University of Manchester.
North Manchester General Hospital, Manchester University NHS Foundation Trust, Manchester.
Eur J Emerg Med. 2022 Dec 1;29(6):413-416. doi: 10.1097/MEJ.0000000000000951. Epub 2022 Sep 6.
Body temperature is considered an independent determinant of respiratory rate and heart rate; however, there is limited scientific evidence regarding the association. This study aimed to assess the association between temperature, and heart rate and respiratory rate in children.
The objective of this study was to validate earlier findings that body temperature causes an increase of approximately 10 bpm rise in heart rate per 1 °C rise in temperature, in children aged under 16 years old.
A prospective study using anonymised prospectively collected patient data of 188 635 attendances, retrospectively extracted from electronic patient records.
Four Emergency or Urgent Care Departments in the North West of England. Participants were children and young people aged 0-16 years old who attended one of the four sites over a period of 3 years.
Multiple linear regression models, adjusted for prespecified confounders (including oxygen saturation, heart rate, respiratory rate, site of attendance, age), were used to examine the influence of various variables on heart rate and respiratory rate.
Among the 235 909 patient visits (median age 5) included, the mean temperature was 37.0 (SD, 0.8). Mean heart rate and respiratory rate were 115.6 (SD, 29.0) and 26.9 (SD, 8.3), respectively. For every 1 °C increase in temperature, heart rate will on average be 12.3 bpm higher (95% CI, 12.2-12.4), after accounting for oxygen saturation, location of attendance, and age. For every 1 °C increase in temperature, there is on average a 0.3% decrease (95% CI, 0.2-0.4%) in respiratory rate.
In this study on children attending urgent and emergency care settings, there was an independent association between temperature and heart rate but not between temperature and respiratory rate.
体温被认为是呼吸率和心率的独立决定因素；然而，关于两者之间的关联，科学证据有限。本研究旨在评估儿童体温与心率和呼吸率之间的关系。
本研究的目的是验证之前的发现，即体温每升高 1°C，儿童的心率平均升高约 10 bpm。
一项使用匿名前瞻性收集的 188635 次就诊患者数据的前瞻性研究，这些数据是从电子患者记录中回顾性提取的。
英格兰西北部的四个急诊或紧急护理部门。参与者为年龄在 0-16 岁之间在四个地点之一就诊的儿童和青少年。
使用多元线性回归模型，调整了预先指定的混杂因素（包括血氧饱和度、心率、呼吸率、就诊地点、年龄），以检查各种变量对心率和呼吸率的影响。
在纳入的 235909 次就诊（中位年龄 5 岁）中，平均体温为 37.0（标准差，0.8）。平均心率和呼吸率分别为 115.6（标准差，29.0）和 26.9（标准差，8.3）。在考虑血氧饱和度、就诊地点和年龄后，体温每升高 1°C，心率平均升高 12.3 bpm（95%置信区间，12.2-12.4）。体温每升高 1°C，呼吸率平均降低 0.3%（95%置信区间，0.2-0.4%）。
在这项针对紧急和紧急护理环境中就诊的儿童的研究中，体温与心率之间存在独立的关联，但体温与呼吸率之间没有关联。
