Beijing National Laboratory for Condensed Matter Physics, Institute of Physics, Chinese Academy of Sciences, Beijing 100190, China; School of Physical Sciences, University of Chinese Academy of Sciences, Beijing 100049, China.
Wenzhou Institute, University of Chinese Academy of Sciences, Wenzhou, Zhejiang 325001, China.
J Colloid Interface Sci. 2022 Oct 15;624:546-554. doi: 10.1016/j.jcis.2022.05.156. Epub 2022 Jun 1.
Graphene-based microparticles materials are broadly utilized in all sorts of fields owing to their outstanding properties. Despite great progress, the present graphene microparticles still face challenges in the aspects of size uniformity, motion flexibility, and tailorable surface chemistry, which limit their application in some specific fields, such as versatile adsorption. Hence, the development of novel graphene microparticles with the aforementioned characteristics is urgently required.
We presented a simple microfluidic electrospray strategy to generate magnetic Janus reduced graphene oxide/carbon (rGO/C) composite microspheres with a variety of unique features. Specifically, the microfluidic electrospray method endowed the obtaiend microspheres with sufficient size uniformity as well as magnetic responsive motion ability. Additionally, magnetic-mediated surface assembly of phase transition lysozyme (PTL) nanofilm on the microspheres rendered the deposited area hydrophilic while non-deposited area hydrophobic.
Such magnetic Janus rGO/C composite microspheres with regionalized wettability characteristics not only showed prominent performance in adsorbing organic liquids with high adsorption capacity and remarkable reusability but also displayed satisfying biocompatibility for the efficient uptake of bilirubin. More encouragingly, the microspheres could serve as adsorbents in a simulative hemoperfusion setup, which further demonstrated the clinical application potential of the magnetic Janus rGO/C microspheres. Thus, we anticipate that the obtained magnetic Janus rGO/C composite microspheres could show multifunctional properties toward water treatment and blood molecule cleaning.
由于其出色的性能，基于石墨烯的微粒材料在各个领域得到了广泛的应用。尽管取得了巨大的进展，但目前的石墨烯微球仍在尺寸均匀性、运动灵活性和可定制表面化学等方面面临挑战，这限制了它们在某些特定领域的应用，如多功能吸附。因此，迫切需要开发具有上述特性的新型石墨烯微球。
我们提出了一种简单的微流控电喷雾策略，以生成具有多种独特特征的磁性各向异性还原氧化石墨烯/碳（rGO/C）复合微球。具体来说，微流控电喷雾方法赋予了所得微球足够的尺寸均匀性和磁响应运动能力。此外，通过磁介导的相变溶菌酶（PTL）纳米膜在微球上的表面组装，使沉积区域亲水而未沉积区域疏水。
这种具有区域化润湿性特征的磁性各向异性 rGO/C 复合微球不仅在吸附高吸附容量和显著可重复使用的有机液体方面表现出突出的性能，而且在有效摄取胆红素方面表现出良好的生物相容性。更令人鼓舞的是，微球可用作模拟血液灌流装置中的吸附剂，进一步证明了磁性各向异性 rGO/C 微球的临床应用潜力。因此，我们预计所获得的磁性各向异性 rGO/C 复合微球在水处理和血液分子净化方面将表现出多功能特性。
