Dawson Luke P, Smith Karen, Cullen Louise, Nehme Ziad, Lefkovits Jeffrey, Taylor Andrew J, Stub Dion
Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, Australia; Department of Cardiology, The Royal Melbourne Hospital, Melbourne, Victoria, Australia; Department of Cardiology, The Alfred Hospital, Melbourne, Victoria, Australia.
Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, Australia; Ambulance Victoria, Melbourne, Victoria, Australia; Department of Paramedicine, Monash University, Melbourne, Victoria, Australia.
J Am Coll Cardiol. 2022 Jun 14;79(23):2333-2348. doi: 10.1016/j.jacc.2022.03.380.
Existing assessment pathways for acute chest pain are often resource-intensive, prolonged, and expensive. In this review, the authors describe existing chest pain pathways and current issues at the patient and system level, and provide an overview of recent advances in chest pain research that could inform improved outcomes for both patients and health systems. There are multiple avenues to improve existing models of chest pain care, including novel risk stratification pathways incorporating highly sensitive point-of-care troponin assays; new devices available before first medical contact that could allow clinicians to access vital signs and electrocardiogram data; artificial intelligence and precision medicine tools that may guide indications for further testing; and strategies to improve hospital benchmarking and performance monitoring to standardize care. Improving the speed and accuracy of chest pain diagnosis and management should be a priority for researchers and is likely to translate to substantive benefits for patients and health systems.
现有的急性胸痛评估途径通常资源消耗大、耗时且昂贵。在本综述中,作者描述了现有的胸痛途径以及患者和系统层面的当前问题,并概述了胸痛研究的最新进展,这些进展可为改善患者和卫生系统的结局提供参考。有多种途径可改善现有的胸痛护理模式,包括纳入高敏即时肌钙蛋白检测的新型风险分层途径;在首次医疗接触前即可使用的新设备,可使临床医生获取生命体征和心电图数据;可能指导进一步检查指征的人工智能和精准医学工具;以及改善医院基准评估和绩效监测以规范护理的策略。提高胸痛诊断和管理的速度和准确性应是研究人员优先考虑的事项,这可能会给患者和卫生系统带来实质性益处。