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索马里摩加迪沙孕妇中 SARS-CoV-2 病毒抗体的血清流行率和社会人口学特征:一项横断面调查研究。

Seroprevalence of SARS-CoV-2 virus antibodies and sociodemographic features of pregnant women in Mogadishu, Somalia: a cross-sectional survey study.

机构信息

Department of Obstetrics and Gynecology, Dr. Sumait Hospital, Faculty of Medicine and Health Sciences, SIMAD University, Mogadishu, Benadir, Somalia.

Department of Nursing and Midwifery, Faculty of Medicine and Health Sciences, SIMAD University, Mogadishu, Benadir, Somalia.

出版信息

BMJ Open. 2022 Jun 9;12(6):e059617. doi: 10.1136/bmjopen-2021-059617.

DOI:10.1136/bmjopen-2021-059617
PMID:35680266
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9185162/
Abstract

OBJECTIVE

Recent investigations have revealed that COVID-19 during pregnancy substantially increases the risk of harmful outcomes for mothers and neonates, including preterm death and stillbirth as well as severe maternal morbidity and mortality. Hence, the urgent need to understand the prevalence rate and level of awareness about COVID-19 (SARS-CoV-2 virus infection) and the practice of preventive measures against the disease among pregnant women in Somalia. This study aims to determine the prevalence of COVID-19 among pregnant women seeking antenatal care in the Benadir region (Mogadishu) of Somalia and to assess their knowledge and preventive practices towards COVID-19.

SETTING

A hospital-based cross-sectional study involving two major referral maternity hospitals in Mogadishu, Somalia.

PARTICIPANTS

Pregnant women seeking antenatal services were included in our study.

METHODS

A total of 477 blood samples were collected from pregnant women attending the two referral hospitals in Mogadishu and screened for COVID-19. The participants were subjected to questionnaire interviews where their detailed history and practice of prevention against COVID-19 were evaluated.

RESULTS

The results showed that 175 (36.7%) were positive while 302 (63.3%) samples were negative for SARS-CoV-2 virus antibodies. Also, out of the 141 pregnant women who had two children or less, 19.4% were positive for IgG/IgM antibodies. Participants who had close contact with patients with COVID-19 were significantly associated for testing positive with a p value 0.0001. Students, teachers, employed people and individuals reported COVID-19 like symptoms were all associated with COVID-19 seropositivity outcomes.

CONCLUSION

Pregnant women and those with commorbidies should be given special preventive care and health education about COVID-19 transmission.

摘要

目的

最近的研究表明,COVID-19 在妊娠期间会显著增加母婴不良结局的风险,包括早产死亡、死产以及严重的孕产妇发病率和死亡率。因此,迫切需要了解 COVID-19(SARS-CoV-2 病毒感染)在索马里孕妇中的流行率和知晓率,以及针对该病的预防措施的实施情况。本研究旨在确定在索马里贝纳迪尔地区(摩加迪沙)寻求产前护理的孕妇中 COVID-19 的流行率,并评估她们对 COVID-19 的知识和预防措施。

背景

这是一项在索马里摩加迪沙的两家主要转诊妇产医院进行的基于医院的横断面研究。

参与者

我们的研究纳入了前来这两家转诊医院就诊的孕妇。

方法

从前来摩加迪沙两家转诊医院就诊的孕妇中采集了 477 份血样,用于筛查 COVID-19。对参与者进行了问卷调查访谈,评估他们的详细病史和预防 COVID-19 的措施。

结果

结果显示,175 份(36.7%)血样呈 SARS-CoV-2 病毒抗体阳性,302 份(63.3%)血样呈 SARS-CoV-2 病毒抗体阴性。此外,在 141 名生育两个或更少子女的孕妇中,19.4%的孕妇 IgG/IgM 抗体阳性。与 COVID-19 患者有密切接触的参与者检测结果呈阳性的可能性显著更高,p 值为 0.0001。与 COVID-19 类似症状的学生、教师、受雇人员和个体均与 COVID-19 血清阳性结果相关。

结论

应向孕妇和合并症患者提供针对 COVID-19 传播的特殊预防保健和健康教育。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75c1/9185162/6a9192dc3625/bmjopen-2021-059617f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75c1/9185162/9cc189e77f86/bmjopen-2021-059617f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75c1/9185162/6a9192dc3625/bmjopen-2021-059617f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75c1/9185162/9cc189e77f86/bmjopen-2021-059617f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75c1/9185162/6a9192dc3625/bmjopen-2021-059617f02.jpg

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