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全球及澳大利亚视角下的羔羊贫血病因

Anaemia in Lambs Caused by : Global and Australian Perspectives.

作者信息

Windsor Peter A

机构信息

Sydney School of Veterinary Science, The University of Sydney, Camden, NSW 2570, Australia.

出版信息

Animals (Basel). 2022 May 27;12(11):1372. doi: 10.3390/ani12111372.

Abstract

(formerly ) is a haemotropic parasitic bacterium found within erythrocytes and distributed widely in global sheep and goat production regions. is transmitted by biting flies and by contaminated instruments, causing morbidity and mortalities from anaemia, usually within 6 weeks following blood-exposure procedures, particularly vaccination, castration, ear tagging, mulesing, and occasionally crutching and shearing. Affected animals develop haemolytic anaemia and may have jaundice, causing abattoir condemnations. The typical history, clinical and pathological findings, display of in blood smears and/or by PCR is diagnostic, although immune responses deplete from smears; hence, in-contact healthy animals should be examined. Differential diagnoses include haemonchosis, fasciolosis, malnutrition (copper or vitamin B12 deficiency), and plant toxicities. parasitaemia may persist, with recrudescence following stressful events, although most older sheep remain immune. Human infections have been reported. Inadequate socioeconomic data present difficulties in assessing the impact of on production and as antimicrobial therapy is ineffective, its control requires management practices that minimize the impact of invasive procedures in periods when risks of transmission are more likely. Although considered an emerging pathogen, recent improvements in welfare attitudes and husbandry practices on Australian sheep farms may potentially limit the transmission of

摘要

(以前称为 )是一种寄生于红细胞内的嗜血性寄生细菌,广泛分布于全球绵羊和山羊养殖地区。它通过吸血蝇和受污染的器械传播,在接触血液的操作(特别是疫苗接种、去势、打耳标、剪羊毛,偶尔还有剪尾和剪毛)后通常在6周内,会因贫血导致发病和死亡。受感染的动物会出现溶血性贫血,可能伴有黄疸,导致屠宰场拒收。典型的病史、临床和病理表现、血液涂片和/或通过聚合酶链反应检测到 即可确诊,尽管免疫反应会使涂片上的 消失;因此,应对接触过的健康动物进行检查。鉴别诊断包括捻转血矛线虫病、肝片吸虫病、营养不良(铜或维生素B12缺乏)和植物中毒。 血症可能会持续存在,在应激事件后复发,不过大多数成年绵羊仍具有免疫力。已有人类感染的报道。由于缺乏足够的社会经济数据,难以评估 对生产的影响,而且抗菌治疗无效,其防控需要采取管理措施,在 传播风险较高的时期尽量减少侵入性操作的影响。尽管被认为是一种新出现的病原体,但澳大利亚绵羊养殖场近期在福利观念和饲养管理方面的改善可能会限制 的传播

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/226a/9179446/21f630a555d8/animals-12-01372-g001.jpg

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