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母犬腹腔镜与开放式卵巢切除术:与手术技术相关的心肺值、血液参数及七氟醚需求的变化

Laparoscopic versus Open Ovariectomy in Bitches: Changes in Cardiorespiratory Values, Blood Parameters, and Sevoflurane Requirements Associated with the Surgical Technique.

作者信息

Fernández-Martín Silvia, Valiño-Cultelli Victoria, González-Cantalapiedra Antonio

机构信息

Rof-Codina Veterinary Teaching Hospital, Faculty of Veterinary, Universidade de Santiago de Compostela, 27002 Lugo, Spain.

Department of Anatomy, Animal Production and Veterinary Clinical Sciences, Faculty of Veterinary, Universidade de Santiago de Compostela, 27002 Lugo, Spain.

出版信息

Animals (Basel). 2022 Jun 2;12(11):1438. doi: 10.3390/ani12111438.

Abstract

The aim of this study was to examine the cardiorespiratory and blood changes associated with pneumoperitoneum (PNP) in laparoscopic ovariectomy (LAP Ove), as well as sevoflurane requirements, comparing them to those determined in open surgery (LPT Ove). The study was performed in 16 bitches submitted to LAP or LPT Ove. The cardiorespiratory and end-tidal sevoflurane concentration values were recorded as follows: at the beginning of surgery (T1), after the right ovary resection (T2), after the left ovary resection (T3), and after surgical closure (T4). Blood samples were taken before and after PNP. Among the cardiorespiratory parameters, no differences were observed in the values of end-tidal CO, minute volume, and heart rate. In the LAP Ove group, a significant increase in inspiratory pressures and a decreased compliance were identified at T2 and T3. Significant higher arterial pressure values were observed in both groups at T2 and T3, with this increase especially marked at T2 in the LPT Ove group. Sevoflurane requirements were significantly higher in the LPT group during ovarian resection. Finally, in terms of the hematochemical parameters, statistical differences were recorded between pre- and post-operative assessments, but not between both surgical groups. The pathophysiological effects associated with PNP seemed to be transient and well-tolerated by healthy dogs.

摘要

本研究旨在探讨腹腔镜卵巢切除术(LAP Ove)中与气腹(PNP)相关的心肺及血液变化,以及七氟醚需求量,并将其与开腹手术(LPT Ove)中的情况进行比较。该研究对16只接受LAP或LPT Ove手术的母犬进行。记录的心肺及呼气末七氟醚浓度值如下:手术开始时(T1)、右侧卵巢切除后(T2)、左侧卵巢切除后(T3)及手术结束后(T4)。在PNP前后采集血样。在心、肺参数方面,呼气末二氧化碳分压、分钟通气量和心率值未观察到差异。在LAP Ove组中,T2和T3时吸气压力显著升高,顺应性降低。两组在T2和T3时动脉压值均显著升高,LPT Ove组在T2时升高尤为明显。卵巢切除期间,LPT组的七氟醚需求量显著更高。最后,在血液生化参数方面,术前和术后评估之间存在统计学差异,但两个手术组之间无差异。与PNP相关的病理生理效应似乎是短暂的,健康犬耐受性良好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/da3f/9179476/a15b580012fd/animals-12-01438-g001.jpg

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