Scott Jacqueline, Singh Ameet, Valverde Alexander
College of Veterinary Medicine, University of Illinois, Urbana-Champaign, IL 61802, USA.
Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, ON N1G 2W1, Canada.
Vet Sci. 2020 May 12;7(2):64. doi: 10.3390/vetsci7020064.
To review the effects of carbon dioxide pneumoperitoneum during laparoscopy, evaluate alternative techniques to establishing a working space and compare this to current recommendations in veterinary surgery Literature review 92 peer-reviewed articles. An electronic database search identified human and veterinary literature on the effects of pneumoperitoneum (carbon dioxide insufflation for laparoscopy) and alternatives with a focus on adaptation to the veterinary field. Laparoscopy is the preferred surgical approach for many human and several veterinary procedures due to the lower morbidity associated with minimally invasive surgery, compared to laparotomy. The establishment of a pneumoperitoneum with a gas most commonly facilitates a working space. Carbon dioxide is the preferred gas for insufflation as it is inert, inexpensive, noncombustible, colorless, excreted by the lungs and highly soluble in water. Detrimental side effects such as acidosis, hypercapnia, reduction in cardiac output, decreased pulmonary compliance, hypothermia and post-operative pain have been associated with a pneumoperitoneum established with CO insufflation. As such alternatives have been suggested such as helium, nitrous oxide, warmed and humidified carbon dioxide and gasless laparoscopy. None of these alternatives have found a consistent benefit over standard carbon dioxide insufflation. The physiologic alterations seen with CO insufflation at the current recommended intra-abdominal pressures are mild and of transient duration. The current recommendations in veterinary laparoscopy for a pneumoperitoneum using carbon dioxide appear to be safe and effective.
回顾腹腔镜检查期间二氧化碳气腹的影响,评估建立工作空间的替代技术,并将其与兽医外科的当前建议进行比较。文献综述:92篇经同行评审的文章。通过电子数据库搜索,确定了关于气腹(用于腹腔镜检查的二氧化碳注入)的影响以及替代方法的人类和兽医文献,重点是适应兽医领域。与剖腹术相比,由于微创手术相关的发病率较低,腹腔镜检查是许多人类和一些兽医手术的首选手术方法。用气体建立气腹最常有助于形成工作空间。二氧化碳是注入的首选气体,因为它是惰性的、便宜的、不可燃的、无色的、由肺排出且高度溶于水。与通过二氧化碳注入建立的气腹相关的有害副作用包括酸中毒、高碳酸血症、心输出量减少、肺顺应性降低、体温过低和术后疼痛。因此,有人提出了替代方法,如氦气、一氧化二氮、温热加湿的二氧化碳和无气腹腔镜检查。这些替代方法均未发现比标准二氧化碳注入有持续一致的益处。在当前推荐的腹内压力下,二氧化碳注入所观察到的生理改变是轻微且持续时间短暂的。兽医腹腔镜检查中目前关于使用二氧化碳进行气腹的建议似乎是安全有效的。