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异种胶原基质在种植体周围软组织增量中的应用:对当前证据和新技术展示的批判性综述

Use of Xenogenic Collagen Matrices in Peri-Implant Soft Tissue Volume Augmentation: A Critical Review on the Current Evidence and New Technique Presentation.

作者信息

De Annuntiis Carlo, Testarelli Luca, Guarnieri Renzo

机构信息

Private Perio-Implant Practive, 00100 Rome, Italy.

Department of Oral and Maxillofacial Sciences, University La Sapienza, 00100 Rome, Italy.

出版信息

Materials (Basel). 2022 May 31;15(11):3937. doi: 10.3390/ma15113937.

DOI:10.3390/ma15113937
PMID:35683237
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9182004/
Abstract

UNLABELLED

Plastic peri-implant surgical procedures aiming to increase soft tissue volume around dental implants have long been well-described. These are represented by: pedicle soft tissue grafts (rotational flap procedures and advanced flap procedures) and free soft tissue grafts (epithelialized, also called free gingival graft (FGG), and non-epithelialized, also called, connective tissue graft (CTG) or a combination of both. To bypass the drawback connected with autologous grafts harvesting, xenogenic collagen matrices (XCM)s and collagen-based matrices derived from porcine dermis (PDXCM)s have been introduced, as an alternative, in plastic peri-implant procedures.

AIM

This review is aimed to evaluate and to critically analyze the available evidence on the effectiveness of XCMs and PDXCMs in soft tissue volume augmentation around dental implants. Moreover, a clinical case with a new soft tissue grafting procedure technique (Guided Soft Tissue Regeneration, GSTR) is presented.

MATERIAL AND METHODS

An electronic search was performed on the MEDLINE database, SCOPUS, Cochrane Library and Web of Science. The electronic search provided a total of 133 articles. One hundred and twenty-eight not meeting the inclusion criteria were excluded. Seven articles of human randomized clinical trials were selected. A total number of 108 patients were treated with CTG, and 110 patients with XCM.

RESULTS

in peri-implant soft tissue augmentation procedures, XCMs seem an effective alternative to CTGs, associated with lower patient morbidity and lower operative times.

摘要

未标注

旨在增加牙种植体周围软组织体积的种植体周围整形手术早已被详细描述。这些手术包括:带蒂软组织移植(旋转瓣手术和推进瓣手术)和游离软组织移植(上皮化的,也称为游离龈移植术(FGG),以及非上皮化的,也称为结缔组织移植术(CTG)或两者结合。为了克服与自体移植采集相关的缺点,已引入异种胶原基质(XCM)和源自猪真皮的胶原基质(PDXCM)作为种植体周围整形手术的替代方法。

目的

本综述旨在评估和批判性分析关于XCM和PDXCM在牙种植体周围软组织增量有效性的现有证据。此外,还介绍了一种采用新的软组织移植手术技术(引导性软组织再生,GSTR)的临床病例。

材料与方法

在MEDLINE数据库、SCOPUS、Cochrane图书馆和科学网进行电子检索。电子检索共获得133篇文章。排除128篇不符合纳入标准的文章。选择了7篇人类随机临床试验文章。共有108例患者接受了CTG治疗,110例患者接受了XCM治疗。

结果

在种植体周围软组织增量手术中,XCM似乎是CTG的有效替代方法,具有较低的患者发病率和较短的手术时间。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8590/9182004/3f74e10d6d89/materials-15-03937-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8590/9182004/a718a87fd0b8/materials-15-03937-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8590/9182004/179f896dd0fe/materials-15-03937-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8590/9182004/059ccd3797f1/materials-15-03937-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8590/9182004/a27db4f89f65/materials-15-03937-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8590/9182004/002c30993195/materials-15-03937-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8590/9182004/3f74e10d6d89/materials-15-03937-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8590/9182004/a718a87fd0b8/materials-15-03937-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8590/9182004/179f896dd0fe/materials-15-03937-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8590/9182004/059ccd3797f1/materials-15-03937-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8590/9182004/a27db4f89f65/materials-15-03937-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8590/9182004/002c30993195/materials-15-03937-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8590/9182004/3f74e10d6d89/materials-15-03937-g006.jpg

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本文引用的文献

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J Clin Periodontol. 2021 Apr;48(4):560-569. doi: 10.1111/jcpe.13426. Epub 2021 Feb 1.
2
The peri-implant phenotype and implant esthetic complications. Contemporary overview.种植体周围表型和种植体美学并发症。当代概述。
J Esthet Restor Dent. 2021 Jan;33(1):212-223. doi: 10.1111/jerd.12709. Epub 2021 Jan 18.
3
Clinical and Histological Differences between Guided Tissue Regeneration with Acellular Dermal Matrix of Porcine Origin and Autologous Connective Tissue: An Animal Study.
首例人体研究:评估微粉化牙龈结缔组织用于种植体周围软组织再生的安全性——一项探索性病例系列研究
Medicines (Basel). 2023 Jan 4;10(1):9. doi: 10.3390/medicines10010009.
猪源脱细胞真皮基质引导组织再生与自体结缔组织的临床及组织学差异:一项动物研究
Materials (Basel). 2021 Jan 7;14(2):272. doi: 10.3390/ma14020272.
4
Volumetric soft tissue alterations in the early healing phase after peri- implant soft tissue contour augmentation with a porcine collagen matrix versus the autologous connective tissue graft: A controlled clinical trial.种植体周围软组织轮廓增加用猪胶原蛋白基质与自体结缔组织移植物在早期愈合阶段的软组织体积变化:一项对照临床试验。
J Clin Periodontol. 2021 Jan;48(1):145-162. doi: 10.1111/jcpe.13387. Epub 2020 Nov 12.
5
Clinical and volumetric analysis of peri-implant soft tissue augmentation using an acellular dermal matrix: A prospective cohort study.使用脱细胞真皮基质进行种植体周围软组织增量的临床和容量分析:一项前瞻性队列研究。
J Periodontol. 2021 Jun;92(6):803-813. doi: 10.1002/JPER.20-0219. Epub 2020 Oct 19.
6
Early implant placement and peri-implant augmentation with a porcine-derived acellular dermal matrix and synthetic bone in the aesthetic area: a 2-year follow-up prospective cohort study.在美学区域中使用猪源去细胞真皮基质和合成骨进行早期种植体植入和种植体周骨增量:一项为期 2 年的前瞻性队列研究。
Int J Oral Maxillofac Surg. 2021 Feb;50(2):258-266. doi: 10.1016/j.ijom.2020.07.002. Epub 2020 Jul 14.
7
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8
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9
The peri-implant phenotype.种植体周围表型。
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10
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J Periodontol. 2020 Aug;91(8):1011-1017. doi: 10.1002/JPER.19-0447. Epub 2020 Feb 6.