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颈动脉支架置入术后认知功能——1年随访研究

Cognitive Functions after Carotid Artery Stenting-1-Year Follow-Up Study.

作者信息

Piegza Magdalena, Jaworska Izabela, Piegza Jacek, Bujak Kamil, Dębski Paweł, Leksowska Aleksandra, Gorczyca Piotr, Gąsior Mariusz, Pudlo Robert

机构信息

Department of Psychiatry, Faculty of Medical Sciences in Zabrze, Medical University of Silesia in Katowice, 42-612 Tarnowskie Gory, Poland.

Department of Cardiac, Vascular and Endovascular Surgery and Transplantology, Silesian Center for Heart Diseases, Medical University of Silesia in Katowice, 41-800 Zabrze, Poland.

出版信息

J Clin Med. 2022 May 27;11(11):3019. doi: 10.3390/jcm11113019.

Abstract

BACKGROUND

The revascularization of carotid arteries minimizes the risk of future cerebral stroke and usually improves cognitive functions. The aim of this study was to assess changes in cognitive function and verify the hypothesis assuming an improvement of selected cognitive functions-psychomotor speed, visuospatial episodic memory, executive function and verbal fluency-in patients after carotid artery stenting during a 12-month follow-up.

METHODS

47 persons subject to CAS, including 13 symptomatic persons, were examined before and 12 months after a procedure with a psychological test battery (digit symbol test-DS, Rey-Osterrieth complex figure test-ROCF, Wisconsin Card Sorting Test-WCST, letter verbal fluency-LVF). Sociodemographic data and clinical parameters were acquired from an author questionnaire.

RESULTS

The one-year follow-up, after the performed CAS procedure, demonstrated a significant improvement of psychomotor speed, visuospatial episodic memory, and executive function. No changes in the area of verbal fluency or decline in any of cognitive functions under analysis were observed.

CONCLUSIONS

Carotid artery stenting improves cognitive functioning, both in the area of basic and more complex cognitive functions in persons with carotid atherosclerosis.

摘要

背景

颈动脉血运重建可将未来发生脑卒的风险降至最低,并通常能改善认知功能。本研究的目的是评估认知功能的变化,并验证假设,即假设在12个月的随访期内,颈动脉支架置入术后患者的某些认知功能(心理运动速度、视觉空间情景记忆、执行功能和语言流畅性)会得到改善。

方法

47例接受颈动脉支架置入术(CAS)的患者,包括13例有症状的患者,在手术前和术后12个月接受了一套心理测试(数字符号测试-DS、雷-奥斯特里思复杂图形测试-ROCF、威斯康星卡片分类测试-WCST、字母语言流畅性-LVF)。社会人口统计学数据和临床参数通过作者问卷获得。

结果

在进行CAS手术后的一年随访中,心理运动速度、视觉空间情景记忆和执行功能有显著改善。未观察到语言流畅性方面的变化或所分析的任何认知功能下降。

结论

颈动脉支架置入术可改善颈动脉粥样硬化患者的认知功能,包括基本认知功能和更复杂认知功能方面。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddd0/9180931/0c89a4989242/jcm-11-03019-g001.jpg

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