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有症状和无症状颈动脉狭窄的医学与外科治疗:一项全面的文献综述

Medical and Surgical Management of Symptomatic and Asymptomatic Carotid Artery Stenosis: A Comprehensive Literature Review.

作者信息

Mohd Ahmed B, Alabdallat Yasmeen, Mohd Omar B, Ghannam Reem A, Sawaqed Seri, Hasan Hanan, Ellebedy Mohamed, Turkmani Khaled, Al-Ezzi Shakir

机构信息

Faculty of Medicine, Hashemite University, Zarqa, JOR.

Infectious Disease, Faculty of Medicine, Hashemite University, Zarqa, JOR.

出版信息

Cureus. 2023 Aug 10;15(8):e43263. doi: 10.7759/cureus.43263. eCollection 2023 Aug.

DOI:10.7759/cureus.43263
PMID:37692579
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10491926/
Abstract

Carotid artery stenosis is a condition where the carotid artery is blocked by fatty cholesterol deposits called plaque, increasing the risk of stroke. Elderly individuals with high cardiovascular risk are more susceptible, along with smokers, those with high cholesterol, males, and older individuals. Young females may also be affected by fibromuscular dysplasia. Carotid stenosis significantly raises stroke risk, and the severity is closely linked to stroke incidence and other cardiovascular events. Early detection and treatment are essential to prevent complications. Treatment options include medical and surgical interventions, such as carotid endarterectomy (CEA) and carotid artery stenting (CAS). The choice between surgery and medical management varies depending on patient characteristics and risk factors. This review explores carotid artery stenosis pathophysiology, risk factors, the importance of early detection and treatment, and the surgical approaches of CEA and CAS, addressing their roles and controversies. Healthcare professionals must understand these aspects to provide optimal care to patients with this condition.

摘要

颈动脉狭窄是一种由于被称为斑块的脂肪胆固醇沉积物阻塞颈动脉而导致的病症,会增加中风风险。心血管风险高的老年人更容易患病,吸烟者、高胆固醇者、男性以及年长者也是如此。年轻女性也可能受纤维肌发育异常影响。颈动脉狭窄会显著提高中风风险,其严重程度与中风发生率及其他心血管事件密切相关。早期检测和治疗对于预防并发症至关重要。治疗选择包括药物和手术干预,如颈动脉内膜切除术(CEA)和颈动脉支架置入术(CAS)。手术与药物治疗之间的选择因患者特征和风险因素而异。本综述探讨了颈动脉狭窄的病理生理学、风险因素、早期检测和治疗的重要性以及CEA和CAS的手术方法,阐述了它们的作用和争议点。医疗保健专业人员必须了解这些方面,以便为患有这种病症的患者提供最佳护理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e84/10491926/0df51ad84c8d/cureus-0015-00000043263-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e84/10491926/2613b3a06058/cureus-0015-00000043263-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e84/10491926/632768bb56d4/cureus-0015-00000043263-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e84/10491926/0df51ad84c8d/cureus-0015-00000043263-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e84/10491926/2613b3a06058/cureus-0015-00000043263-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e84/10491926/632768bb56d4/cureus-0015-00000043263-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e84/10491926/0df51ad84c8d/cureus-0015-00000043263-i03.jpg

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J Clin Med. 2022 May 27;11(11):3019. doi: 10.3390/jcm11113019.
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Editor's Choice - European Society for Vascular Surgery (ESVS) 2023 Clinical Practice Guidelines on the Management of Atherosclerotic Carotid and Vertebral Artery Disease.编辑推荐——欧洲血管外科学会(ESVS)2023年动脉粥样硬化性颈动脉和椎动脉疾病管理临床实践指南
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Cognitive Functions in Patients after Carotid Artery Revascularization-A Narrative Review.
Neurovascular management of intracranial internal carotid artery dissection post-carotid endarterectomy: A case report of an innovative approach.
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Brain Circ. 2024 Dec 28;10(4):366-371. doi: 10.4103/bc.bc_59_24. eCollection 2024 Oct-Dec.
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Chitinase-3-like Protein 1 Reduces the Stability of Atherosclerotic Plaque via Impairing Macrophagic Efferocytosis.几丁质酶-3样蛋白1通过损害巨噬细胞的胞葬作用降低动脉粥样硬化斑块的稳定性。
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