Sugaya N, Takeuchi Y, Kanno T
Clin Chem. 1987 May;33(5):661-3.
We determined lactate dehydrogenase (LD; EC 1.1.1.27) in serum from 75 sequential measles patients and 105 control patients. In the measles patients, LD was increased to 1147.9 +/- 43.8 (mean +/- SE) U/L, markedly more than in the control group (517.2 +/- 15.0 U/L, p less than 0.001). Both LD-3 and LD-4 isoenzymes were increased, but the concentration of LD-5 was normal. Patients with high LD values (greater than 1500 U/L) had longer hospital stays than did those with lower values (p less than 0.01). Our results suggest that increased LD in serum is a common finding in measles infection and presumably originates from lymphocytes.
我们测定了75例连续麻疹患者及105例对照患者血清中的乳酸脱氢酶（LD；EC 1.1.1.27）。麻疹患者的LD升高至1147.9±43.8（均值±标准误）U/L，显著高于对照组（517.2±15.0 U/L，p<0.001）。LD-3和LD-4同工酶均升高，但LD-5的浓度正常。LD值高（大于1500 U/L）的患者住院时间比LD值低的患者更长（p<0.01）。我们的结果表明，血清中LD升高是麻疹感染中的常见现象，可能源于淋巴细胞。
