Bayartai Munkh-Erdene, Luomajoki Hannu, De Micheli Roberta, Tringali Gabriella, Marazzi Nicoletta, Sartorio Alessandro
Institute of Physiotherapy, School of Health Professions, Zurich University of Applied Sciences, 8400 Winterthur, Switzerland.
Department of Physical Therapy, School of Nursing, Mongolian National University of Medical Sciences, Ulaanbaatar 14210, Mongolia.
J Clin Med. 2022 Jun 2;11(11):3175. doi: 10.3390/jcm11113175.
The aim of this study was to examine the short-term changes in disability after an inpatient, multidisciplinary body weight reduction program (BWRP) in adults with obesity. A total of 160 individuals (males: 52, females: 108, BMI > 35 kg/m2) hospitalized for a 3-week multidisciplinary BWRP were recruited into the study. Body composition, lower limb muscle power, fatigue severity, and disability were measured at the beginning and end of the intervention by means of bioimpedance analysis, a stair climbing test (SCT), the Fatigue Severity Scale (FSS), and the Oswestry disability index (ODI), respectively. At the end of the 3-week BWRP, an average body weight reduction of 5.0 kg (CI 95% −5.3; −4.6, p < 0.001) was determined, as well as an improvement in all parameters measured. Clinically meaningful reductions in disability were observed in the moderate disability (Δ = −11.8% CI 95% −14.3; −9.3, p < 0.001) and severe disability (Δ = −15.9% CI 95% −19.6; −12.2, p < 0.001) groups. Reductions in disability were explained only by improvements in the SCT (Δ = −2.7 CI 95% −4.1; −1.4, p < 0.001) and the FSS (Δ = −0.3% CI 95% −0.4; −0.1, p < 0.001). These findings demonstrate the importance of incorporating approaches into a BWRP that increase lower limb muscle power and decrease fatigue severity and thus reduce disability in adults with obesity.
本研究的目的是调查肥胖成年人在接受住院多学科体重减轻计划（BWRP）后残疾情况的短期变化。共有160名因为期3周的多学科BWRP而住院的个体（男性52名，女性108名，BMI>35 kg/m²）被纳入本研究。在干预开始和结束时，分别通过生物电阻抗分析、爬楼梯测试（SCT）、疲劳严重程度量表（FSS）和奥斯威斯利残疾指数（ODI）测量身体成分、下肢肌肉力量、疲劳严重程度和残疾情况。在为期3周的BWRP结束时，确定平均体重减轻了5.0 kg（95%CI -5.3；-4.6，p<0.001），并且所有测量参数均有所改善。在中度残疾组（Δ=-11.8%，95%CI -14.3；-9.3，p<0.001）和重度残疾组（Δ=-15.9%，95%CI -19.6；-12.2，p<0.001）中观察到残疾情况有具有临床意义的改善。残疾情况的改善仅由SCT（Δ=-2.7，95%CI -4.1；-1.4，p<0.001）和FSS（Δ=-0.3%，95%CI -0.4；-0.1，p<0.001）的改善来解释。这些发现证明了在BWRP中纳入能够增加下肢肌肉力量、降低疲劳严重程度从而减少肥胖成年人残疾情况的方法的重要性。
