Sartorio A, Fontana P, Trecate L, Lafortuna C L
Experimental Laboratory of Endocrinological Research, Italian Institute for Auxology, IRCCS, Milan, Italy.
Diabetes Nutr Metab. 2003 Apr;16(2):88-93.
The effects of a short-term (3-week) integrated body weight reduction (BWR) program on fatigue perception and on lower limb anaerobic power output were evaluated in 200 severely obese in-patients (40 males and 160 females, age: 18-83 yr, BMI: 35.0-65.3 kg/m2). Fatigue was assessed by a 7-point Likert-type scale questionnaire (Fatigue Severity Scale, FSS), while average lower limb power output (W) during a maximal effort was determined with a modification of the Margaria test for stair climbing. In both genders, total FSS score was influenced by both age and obesity level, resulting significantly (p < 0.001) lower in younger subjects (< 45 yr) than in older (> 45 yr) and in patients with lower BMI (< 40 kg/m2) than in those with a higher one (> 40 kg/m2). An opposite trend was observed in W. The 3-week BWR integrated program with moderate aerobic exercise and free standing and ground gymnastic routines induced a significant reduction in body weight (p < 0.001), in total FSS score (p < 0.001) and a significant increase in W, both in absolute terms (p < 0.05) and relative to body mass (p < 0.001). Total FSS score and absolute or relative power output were positively correlated both before and after the BWR program (p < 0.001, Wilcoxon rank test). It is concluded that: a) subjective fatigue perception, assessed by a FSS questionnaire, can be considered an indirect indicator of effective lower limb power output in severely obese patients and, b) in spite of a relatively small, although significant, decline of BMI, the full-time participation in a hospital-based, integrated BWR program with moderate exercise activity is associated with significant short-term improvements of both fatigue sensation and power output. Dia
在200名重度肥胖住院患者（40名男性和160名女性，年龄：18 - 83岁，BMI：35.0 - 65.3kg/m²）中评估了短期（3周）综合体重减轻（BWR）计划对疲劳感知和下肢无氧功率输出的影响。通过7点李克特量表问卷（疲劳严重程度量表，FSS）评估疲劳，同时通过对楼梯攀爬的马加里亚测试进行修改来确定最大努力时的平均下肢功率输出（瓦特）。在男性和女性中，FSS总分均受年龄和肥胖程度影响，结果显示，年龄小于45岁的受试者比年龄大于45岁的受试者显著更低（p < 0.001），BMI低于40kg/m²的患者比BMI高于40kg/m²的患者显著更低（p < 0.001）。在瓦特方面观察到相反的趋势。为期3周的BWR综合计划，包括适度有氧运动、自由站立和地面体操训练，导致体重显著减轻（p < 0.001）、FSS总分显著降低（p < 0.001），并且瓦特显著增加，无论是绝对值（p < 0.05）还是相对于体重（p < 0.001）。在BWR计划前后，FSS总分与绝对或相对功率输出均呈正相关（p < 0.001，威尔科克森秩和检验）。得出以下结论：a）通过FSS问卷评估的主观疲劳感知可被视为重度肥胖患者有效下肢功率输出的间接指标；b）尽管BMI有相对较小但显著的下降，但全职参与基于医院的、包含适度运动活动的综合BWR计划与疲劳感和功率输出的显著短期改善相关。
