Elawady Sameh Samir, Phuyal Diwakar, Shah Rakesh Kumar, Mirza Lubna
Faculty of Medicine, Tanta University, Tanta, Egypt.
Kirtipur Hospital, PHECT Nepal, Kathmandu, Nepal.
Case Rep Endocrinol. 2022 May 31;2022:2211061. doi: 10.1155/2022/2211061. eCollection 2022.
/. Since the start of the pandemic, COVID-19 has been associated with several postinfection complications. Subacute thyroiditis (SAT) is an inflammatory disorder of the thyroid that has been reported in the literature following COVID-19 infection. We report a case of SAT following COVID-19 infection. . A 33-year-old female presented with neck pain two weeks after resolution of COVID-19 infection. Her thyroid function tests together with ultrasonographic pictures were consistent with SAT. She was treated with three rounds of medrol dose pack without relief. She then required oral prednisone 40 mg per day and ibuprofen 800 mg once daily for another several weeks that eventually resulted in improvement of her symptoms. . SAT most commonly occurs in females during or after viral infection. The usual course of the disease is hyperthyroidism then hypothyroidism followed by resolution. SAT is clinically diagnosed by lab findings of decreased TSH in the setting of negative thyroid-stimulating and thyroid peroxidase antibodies. All these data are consistent with our case. . SAT following COVID-19 infection presents with a similar clinical presentation and course as the classic form of SAT, but we should consider the fact that a high-dose corticosteroid treatment might be necessary for such patients.
自疫情开始以来，新型冠状病毒肺炎（COVID-19）与多种感染后并发症相关。亚急性甲状腺炎（SAT）是一种甲状腺炎症性疾病，文献中已有COVID-19感染后发生该疾病的报道。我们报告一例COVID-19感染后发生的SAT病例。一名33岁女性在COVID-19感染症状消退两周后出现颈部疼痛。她的甲状腺功能检查及超声图像与SAT相符。她接受了三轮美卓乐冲击治疗但症状未缓解。随后她需要每天口服40毫克泼尼松及每天一次800毫克布洛芬，持续数周，最终症状得到改善。SAT最常见于病毒感染期间或之后的女性。该病通常病程为甲亢期然后甲减期，随后缓解。SAT通过甲状腺刺激抗体和甲状腺过氧化物酶抗体阴性情况下促甲状腺激素（TSH）降低的实验室检查结果进行临床诊断。所有这些数据与我们的病例一致。COVID-19感染后发生的SAT与经典形式的SAT临床表现和病程相似，但我们应考虑到此类患者可能需要大剂量皮质类固醇治疗这一事实。
