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泰国新冠疫情期间及之前,针对医护人员和患者的局部感染控制方案下白内障手术的安全性和有效性:来自二级中心的前瞻性队列研究

Safety and Efficacy of Cataract Surgery Under a Local Infection Control Protocol Before and During a COVID-19 Wave in Thailand for Healthcare Workers and Patients: A Prospective Cohort from a Secondary Center.

作者信息

Rujkorakarn Ploysai, Patamatamkul Samadhi

机构信息

Department of Ophthalmology, Suddhavej Hospital, Faculty of Medicine, Mahasarakham University, Mahasarakham, Thailand.

Department of Internal Medicine, Suddhavej Hospital, Faculty of Medicine, Mahasarakham University, Mahasarakham, Thailand.

出版信息

Clin Ophthalmol. 2022 Jun 3;16:1773-1781. doi: 10.2147/OPTH.S366353. eCollection 2022.

Abstract

PURPOSE

To assess the effectiveness of a local infection control protocol for cataract surgery (CS) during the coronavirus disease (COVID-19) pandemic and determine the trend of CSs and visual outcomes during this period, as compared to the pre-COVID-19 pandemic period.

METHODS

This study was conducted at Suddhavej Hospital, Mahasarakham University, Mahasarakham, Thailand, between July 1, 2020, and March 31, 2021. In this two-phase study, we used only a COVID-19-screening questionnaire during the first phase and preoperative nasopharyngeal swab severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) testing for real-time reverse transcriptase-polymerase chain reaction in the second phase, during Thailand's second COVID-19 wave. Nasopharyngeal swab SARS-CoV-2 nucleic acid testing, SARS-CoV-2 IgG/IgM, or anti-SARS-CoV-2 spike antibody seroconversion was used to detect COVID-19 infection among healthcare workers. We also compared cataract surgical volume and postoperative visual acuity of CS patients between the pre-COVID-19 period and during the COVID-19 pandemic period.

RESULTS

A total of 947 patients underwent CS. Thirty-two healthcare workers and 275 patients tested negative for SARS-CoV-2 in the second study phase. CSs increased on average by 50.09% month-to-month when the surgery was resumed. The mean postoperative logMAR best-corrected visual acuity was significantly better in the COVID-19 pandemic period than in the pre-pandemic period (difference, 0.1 [95% CI: 0.00-0.12], p < 0.0001).

CONCLUSION

CS could be safely performed under an infection control protocol during the COVID-19 pandemic. The cataract surgical volume, with favorable visual outcomes, has an increasing trend after resuming elective surgeries.

摘要

目的

评估在冠状病毒病(COVID-19)大流行期间白内障手术(CS)局部感染控制方案的有效性,并确定与COVID-19大流行前时期相比,该时期CS的手术量趋势和视觉效果。

方法

本研究于2020年7月1日至2021年3月31日在泰国玛哈沙拉堪府玛哈沙拉堪大学苏达韦杰医院进行。在这项两阶段研究中,在第一阶段我们仅使用COVID-19筛查问卷,在第二阶段,即在泰国第二波COVID-19疫情期间,对术前鼻咽拭子进行严重急性呼吸综合征冠状病毒2(SARS-CoV-2)实时逆转录聚合酶链反应检测。使用鼻咽拭子SARS-CoV-2核酸检测、SARS-CoV-2 IgG/IgM或抗SARS-CoV-2刺突抗体血清转化来检测医护人员中的COVID-19感染情况。我们还比较了COVID-19大流行前时期和COVID-19大流行期间CS患者的白内障手术量和术后视力。

结果

共有947例患者接受了CS。在第二项研究阶段,32名医护人员和275例患者的SARS-CoV-2检测呈阴性。恢复手术后,CS的手术量平均每月增加50.09%。COVID-19大流行期间术后平均logMAR最佳矫正视力显著优于大流行前时期(差值为0.1 [95% CI:0.00 - 0.12],p < 0.0001)。

结论

在COVID-19大流行期间,CS可以在感染控制方案下安全进行。恢复择期手术后,白内障手术量呈上升趋势,且视觉效果良好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3112/9173727/33dd80bb146a/OPTH-16-1773-g0001.jpg

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