Vafaei Zamaneh, Najafian Jamshid, Shekarchizadeh Masood, Mostafavi Samaneh, Darakhshandeh Ali, Khosravifarsani Mohammadreza, Ashrafi Farzaneh, Sharifi Mehran, Mohammadifard Noushin, Emami Mohammad Hassan, Haghjooy-Javanmard Shaghayegh, Sarrafzadegan Nizal
Isfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
Hypertension Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
ARYA Atheroscler. 2021 Nov;17(6):1-10. doi: 10.22122/arya.v17i0.2212.
Understanding the close interaction between the specialties of cardiology and oncology is necessary for early detection of cardiovascular disease (CVD) events in cancer patients. For the risk assessment of CVD in Breast and Colorectal Cancers (CIBC) study, in the current study we aimed to validate a questionnaire for the assessment of clinical history in patients with breast cancer and colorectal cancer (CRC).
We determined the content validity of the questionnaire using the 2 indexes of content validity ratio (CVR) and content validity index (CVI) to examine the specificity, simplicity, clarity, and transparency of the items. Content validity assessment was performed through a panel of experts including 2 oncologists, 5 cardiologists, 2 general practitioners, and 1 epidemiologist. The reliability of the questionnaire was estimated using Cronbach's alpha coefficient in 50 patients. Intraclass correlation coefficient (ICC) was used to examine the reproducibility of the questionnaire during 1 week.
The CRC and breast cancer questionnaire were designed with 16 and 32 questions, respectively. To obtain acceptable CVR, 5 and 11 questions were removed from the CRC and breast cancer questionnaires, respectively. Cronbach's alpha was 0.70 in the breast cancer questionnaire and 0.94 in the CRC questionnaire. All questions had a CVI of higher than 80%. The ICC in the breast cancer questionnaire ranged between 0.71 and 0.96 and in CRC questionnaire ranged between 0.78 and 0.98.
The validity and reliability of our newly developed questionnaire was desirable. The reliability of the breast cancer questions was acceptable and that of the CRC questions was excellent. Thus, thus questionnaire can be used in this group of patients regardless of whether the goal is cardiac care or not.
了解心脏病学和肿瘤学专业之间的密切相互作用对于早期发现癌症患者的心血管疾病（CVD）事件至关重要。在乳腺癌和结直肠癌（CIBC）的心血管疾病风险评估研究中，在本研究中，我们旨在验证一份用于评估乳腺癌和结直肠癌（CRC）患者临床病史的问卷。
我们使用内容效度比（CVR）和内容效度指数（CVI）这两个指标来确定问卷的内容效度，以检查项目的特异性、简单性、清晰度和透明度。通过包括2名肿瘤学家、5名心脏病学家、2名全科医生和1名流行病学家的专家小组进行内容效度评估。在50名患者中使用Cronbach's α系数估计问卷的信度。组内相关系数（ICC）用于检查问卷在1周内的可重复性。
CRC问卷和乳腺癌问卷分别设计了16个和32个问题。为了获得可接受的CVR，分别从CRC问卷和乳腺癌问卷中删除了5个和11个问题。乳腺癌问卷的Cronbach's α为0.70，CRC问卷的为0.94。所有问题的CVI均高于80%。乳腺癌问卷的ICC在0.71至0.96之间，CRC问卷的ICC在0.78至0.98之间。
我们新开发的问卷的效度和信度是理想的。乳腺癌问题的信度可以接受，CRC问题的信度非常好。因此，无论目标是否是心脏护理，该问卷均可用于这组患者。
