Department of Spinal Surgery, Dongying Shengli Oilfield Central Hospital, Dongying City 257100, Shandong Province, China.
Department of Reproductive Medicine, Dongying Shengli Oilfield Central Hospital, Dongying City 257100, Shandong Province, China.
Contrast Media Mol Imaging. 2022 May 26;2022:5847589. doi: 10.1155/2022/5847589. eCollection 2022.
To explore the diagnostic value of emission computed tomography (ECT) combined with computed tomography (CT) for metastatic malignant tumor of spine.
By means of retrospective study, a total of 102 patients with extraskeletal primary malignant tumor treated in our hospital from February 2019 to February 2021 were selected as the subjects. All patients had single lesion of the spine, of which 72 were malignant and 30 were benign according to the results of pathological examination. ECT and CT examinations were performed to all patients, and by taking the pathological findings as the gold standard, the sensitivity, specificity, positive predictive value and negative predictive value of ECT, CT, and their combination were calculated, and their efficacy in diagnosing metastatic malignant tumor of spine was analyzed.
A total of 68 (94.4%) metastatic malignant spinal tumors were detected by ECT combined with CT, with a detection rate of 100% in breast cancer and lung cancer, 94.1% in liver cancer, and 78.6% in prostate cancer, respectively; the combined diagnosis had a diagnostic sensitivity of 94.4%, specificity of 73.3%, positive predictive value of 89.5%, negative predictive value of 84.6%, and diagnostic accuracy rate of 88.2%, and AUC (95% CI) = 0.839 (0.739-0.939).
Combining ECT with CT has a good diagnostic efficacy for metastatic malignant spinal tumors.
探讨发射型计算机断层扫描（ECT）结合计算机断层扫描（CT）对脊柱转移恶性肿瘤的诊断价值。
采用回顾性研究方法，选取 2019 年 2 月至 2021 年 2 月我院收治的 102 例骨外原发性恶性肿瘤患者为研究对象，所有患者均为单节段脊柱病变，根据病理检查结果，72 例为恶性，30 例为良性。对所有患者进行 ECT 和 CT 检查，以病理结果为金标准，计算 ECT、CT 及其联合检查诊断脊柱转移恶性肿瘤的灵敏度、特异度、阳性预测值和阴性预测值，并分析其诊断效能。
ECT 联合 CT 共检出 68 例（94.4%）脊柱转移恶性肿瘤，乳腺癌、肺癌的检出率为 100%，肝癌为 94.1%，前列腺癌为 78.6%；联合诊断的灵敏度为 94.4%，特异度为 73.3%，阳性预测值为 89.5%，阴性预测值为 84.6%，诊断准确率为 88.2%，AUC（95%CI）为 0.839（0.739-0.939）。
ECT 联合 CT 对脊柱转移恶性肿瘤具有较好的诊断效果。
