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本文引用的文献

1
Recurrent Frameshift Neoantigen Vaccine Elicits Protective Immunity With Reduced Tumor Burden and Improved Overall Survival in a Lynch Syndrome Mouse Model.复发性移码新抗原疫苗在林奇综合征小鼠模型中可引发保护性免疫，减少肿瘤负担并提高总生存率。
Gastroenterology. 2021 Oct;161(4):1288-1302.e13. doi: 10.1053/j.gastro.2021.06.073. Epub 2021 Jul 2.
2
Vaccines for immunoprevention of cancer.癌症免疫预防疫苗。
J Clin Invest. 2021 May 3;131(9). doi: 10.1172/JCI146956.
3
The Role of Antigen Spreading in the Efficacy of Immunotherapies.抗原扩散在免疫疗法中的作用。
Clin Cancer Res. 2020 Sep 1;26(17):4442-4447. doi: 10.1158/1078-0432.CCR-20-0305. Epub 2020 May 1.
4
Immune evasion before tumour invasion in early lung squamous carcinogenesis.肿瘤侵袭前的早期肺鳞癌免疫逃逸。
Nature. 2019 Jul;571(7766):570-575. doi: 10.1038/s41586-019-1330-0. Epub 2019 Jun 26.
5
Discovery and characterization of actionable tumor antigens.发现和鉴定有治疗作用的肿瘤抗原。
Genome Med. 2019 Apr 30;11(1):29. doi: 10.1186/s13073-019-0642-x.
6
The Making of a PreCancer Atlas: Promises, Challenges, and Opportunities.《癌前图谱的绘制：前景、挑战与机遇》
Trends Cancer. 2018 Aug;4(8):523-536. doi: 10.1016/j.trecan.2018.06.007. Epub 2018 Jul 21.
7
Leveraging premalignant biology for immune-based cancer prevention.利用癌前生物学进行基于免疫的癌症预防。
Proc Natl Acad Sci U S A. 2016 Sep 27;113(39):10750-8. doi: 10.1073/pnas.1608077113. Epub 2016 Sep 16.
8
Safety, efficacy, and immunogenicity of VGX-3100, a therapeutic synthetic DNA vaccine targeting human papillomavirus 16 and 18 E6 and E7 proteins for cervical intraepithelial neoplasia 2/3: a randomised, double-blind, placebo-controlled phase 2b trial.VGX-3100用于治疗宫颈上皮内瘤变2/3的安全性、有效性及免疫原性：一项针对人乳头瘤病毒16和18 E6及E7蛋白的治疗性合成DNA疫苗的随机、双盲、安慰剂对照2b期试验
Lancet. 2015 Nov 21;386(10008):2078-2088. doi: 10.1016/S0140-6736(15)00239-1. Epub 2015 Sep 17.
9
Breakthrough of the year 2013. Cancer immunotherapy.2013年度重大突破。癌症免疫疗法。
Science. 2013 Dec 20;342(6165):1432-3. doi: 10.1126/science.342.6165.1432.
10
Vaccination against HPV-16 oncoproteins for vulvar intraepithelial neoplasia.针对人乳头瘤病毒16型癌蛋白的疫苗用于外阴上皮内瘤变
N Engl J Med. 2009 Nov 5;361(19):1838-47. doi: 10.1056/NEJMoa0810097.

Editorial: Cancer Prevention: Targeting Premalignant Epithelial Neoplasms in the Era of Cancer Immunotherapy and Vaccines.

作者信息

Çuburu Nicolas, Finn Olivera J, Van Der Burg Sjoerd H

机构信息

Laboratory of Cellular Oncology, Center for Cancer Research, National Cancer Institute (NIH), Bethesda, MA, United States.

Department of Immunology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, United States.

出版信息

Front Immunol. 2022 May 24;13:924099. doi: 10.3389/fimmu.2022.924099. eCollection 2022.

DOI:10.3389/fimmu.2022.924099
PMID:35686125
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9171359/
Abstract
摘要