Amiraian Dana, McDonough Michelle, Geiger Xochiquetzal
Radiology, Mayo Clinic, Jacksonville, USA.
Laboratory Medicine and Pathology, Mayo Clinic, Jacksonville, USA.
Cureus. 2022 May 4;14(5):e24731. doi: 10.7759/cureus.24731. eCollection 2022 May.
Myeloid sarcoma is a solid extramedullary mass of immature myeloid cells, often in patients with myeloid leukemia. Myeloid sarcoma of the breast is extremely uncommon, and bilateral involvement is even rarer. Myeloid sarcoma of the breast can mimic primary breast cancer, lymphoma, and other neoplasms. Differentiation between myeloid sarcoma and primary breast malignancy is imperative, as management and treatment are drastically different. We present a case of myeloid sarcoma of both breasts in a 63-year-old female with relapsed acute myelogenous leukemia (AML), a personal history of ovarian cancer, and a family history of both leukemia and breast cancer. This report highlights the need for high clinical, radiological, and pathological suspicion to diagnose myeloid sarcoma of the breast.
髓系肉瘤是一种由未成熟髓系细胞构成的实体性髓外肿块，常见于髓系白血病患者。乳腺髓系肉瘤极为罕见，双侧受累更为罕见。乳腺髓系肉瘤可酷似原发性乳腺癌、淋巴瘤及其他肿瘤。由于管理和治疗方法截然不同，因此区分髓系肉瘤与原发性乳腺恶性肿瘤至关重要。我们报告一例63岁女性双侧乳腺髓系肉瘤病例，该患者患有复发性急性髓系白血病（AML），有卵巢癌个人史，且有白血病和乳腺癌家族史。本报告强调了对乳腺髓系肉瘤进行诊断时需要高度的临床、放射学和病理学怀疑。
