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预测眶周坏死性筋膜炎的严重程度。

Predicting severity of periorbital necrotizing fasciitis.

作者信息

Rothschild Michael I, Pacheco Richard R, Wladis Edward J

机构信息

Department of Ophthalmology, Ophthalmic Plastic Surgery, Lions Eye Institute, Albany Medical College, Albany, New York, USA.

Albany Medical College, Albany, New York, USA.

出版信息

Orbit. 2023 Jun;42(3):228-232. doi: 10.1080/01676830.2022.2087231. Epub 2022 Jun 10.

DOI:10.1080/01676830.2022.2087231
PMID:35686501
Abstract

PURPOSE

To determine whether severity of periorbital necrotizing fasciitis can be predicted based on premorbid patient characteristics.

METHODS

Records of 10 consecutive patients with periorbital necrotizing fasciitis presenting at a single center, treated by one attending ophthalmic plastic surgeon, were retrospectively reviewed. Demographic information and medical history were used to determine a Charlson Comorbidity Index (CCI) score for each patient. Other variables included presenting visual acuity, number of surgical debridements performed, infectious organism (if known), and visual acuity at last follow-up. Data were compared with Mann-Whitney U test to determine correlation between variables, using -values as outcome measures.

RESULTS

Increased age at presentation correlated with worse presenting and final visual acuity, requiring more surgical debridements to control disease (each  < .0001). Worse initial visual acuity correlated with need for increased number of debridements ( = .002), but increased number of debridements did not correlate with final visual acuity ( = .101). CCI did not correlate with initial vision ( = .30), final vision ( = .72), or number of surgical debridements necessary ( = .99). Presenting visual acuity did not correlate with final visual acuity ( = .268).

CONCLUSION

Older patients have more severe cases of periorbital necrotizing fasciitis, as defined by increased number of surgeries required to control disease and worse visual outcomes. CCI did not correlate with severity of disease.

摘要

目的

确定是否可以根据患者病前特征预测眶周坏死性筋膜炎的严重程度。

方法

回顾性分析在单一中心由一名眼科整形主治医生治疗的10例连续眶周坏死性筋膜炎患者的记录。利用人口统计学信息和病史确定每位患者的查尔森合并症指数(CCI)评分。其他变量包括就诊时视力、手术清创次数、感染病原体(若已知)以及最后一次随访时的视力。使用Mann-Whitney U检验比较数据以确定变量之间的相关性,以P值作为结果指标。

结果

就诊时年龄增加与就诊时及最终视力较差相关,需要更多的手术清创来控制病情(每项P < 0.0001)。初始视力较差与清创次数增加的需求相关(P = 0.002),但清创次数增加与最终视力无关(P = 0.101)。CCI与初始视力(P = 0.30)、最终视力(P = 0.72)或所需手术清创次数无关(P = 0.99)。就诊时视力与最终视力无关(P = 0.268)。

结论

按照控制病情所需手术次数增加及视力预后较差来定义,老年患者的眶周坏死性筋膜炎病情更严重。CCI与疾病严重程度无关。

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