Becker J T, Boller F, Saxton J, McGonigle-Gibson K L
Cortex. 1987 Mar;23(1):59-72. doi: 10.1016/s0010-9452(87)80019-9.
Recent work has suggested that patients with damage to temporal lobe structures, such as patients with Alzheimer's Disease (AD), lose information from memory at an abnormally rapid rate. In contrast, data from other studies suggest that the rate of forgetting in AD is normal. In the present study, 62 patients with mild to moderate AD and 64 elderly controls were tested for their immediate and delayed recall of a short verbal passage and a modified Rey complex figure. The results suggest that although AD patients recalled less than controls, they did not forget at a faster rate during the 30 minute retention interval, supporting the finding that these memory impaired patients do not have an abnormal rate of forgetting. The data also suggest that poor initial encoding of the stimuli may be the cause of the AD patients' impaired recall.
近期研究表明，颞叶结构受损的患者，如阿尔茨海默病（AD）患者，会以异常快的速度从记忆中丢失信息。相比之下，其他研究的数据表明AD患者的遗忘速度是正常的。在本研究中，对62名轻度至中度AD患者和64名老年对照者进行了测试，以考察他们对一段简短文字段落和一幅改良版雷氏复杂图形的即时和延迟回忆。结果表明，尽管AD患者的回忆量少于对照者，但在30分钟的保持间隔期内，他们的遗忘速度并不更快，这支持了这些记忆受损患者没有异常遗忘速度这一发现。数据还表明，刺激的初始编码不佳可能是AD患者回忆受损的原因。
