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INDICATE 膝关节期望调查旨在发现全膝关节置换术的一般患者治疗目标,以及人口统计学因素对患者期望的影响。

The INDICATE Knee expectations survey detects general patient treatment goals for total knee arthroplasty and the influence of demographic factors on patients expectations.

机构信息

Department of Orthopedics and Traumatology, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.

Institute of Medical Biostatistics, Epidemiology and Informatics, University Medical Center of the Johannes Gutenberg University Mainz, Langenbeckstrasse 1, 55131, Mainz, Germany.

出版信息

Knee Surg Sports Traumatol Arthrosc. 2023 Mar;31(3):892-904. doi: 10.1007/s00167-022-07012-4. Epub 2022 Jun 10.

Abstract

PURPOSE

Post-operative outcome after total knee arthroplasty (TKA) in the treatment of end-stage osteoarthritis correlates strongly with pre-operative impairment-driven patient treatment goals. However, a clinical tool for measuring patient treatment goals in correlation to impairments is still missing, which impedes patient-oriented indication in TKA.

METHODS

Patients scheduled for TKA were recruited in four German hospitals. All patients were handed the INDICATE Knee Score pre-operatively. The score contains 31 treatment goals with respective impairments, subdivided into seven categories. They were asked to rank all treatment goals and impairments on a 3-point scale. Treatment goals and impairments were then checked for frequency of occurrence. Correlation of goal and impairment was tested. Analysis for associations of treatment goals and different cohort characteristics (age, sex, BMI) was conducted.

RESULTS

1.298 patients were included in the study. Seven treatment goals were categorised as "main goal" from more than 90% of all patients ("knee pain", "range of motion", "walking distance", "overall physical function", "climbing stairs", "quality of life", "implant survival"). Comparing age groups, there were significant associations towards higher expectations regarding working, physical and sports related treatment goals in younger patients (< 65y) ("ability to work" (P ≤ .001), "sports activities" (P ≤ .001), "sex life" (P ≤ .001), "dependence on help of others" (P = .015), "preventing secondary impairment" (P = .03), "dependence on walking aids" (P = .005)). Higher BMI resulted in increasing relevance of "weight reduction" (P ≤ .001), "climbing stairs" (P = .039) "global health status" (P = .015) and "long standing" (P = .007) as a "main goal". Analysis for differences in treatment goals regarding sex showed women choosing more treatment goals as "main goals" than men.

CONCLUSION

Seven treatment goals which were expected by > 90% in our collective can be classified as general treatment goals for TKA. Demographic factors (age, sex, BMI) were significantly associated with patients' expectations for TKA. We conclude physicians should clearly assess their patients' demands prior to TKA to maximise post-operative outcome.

LEVEL OF EVIDENCE

Prognostic Level III.

摘要

目的

全膝关节置换术(TKA)治疗终末期骨关节炎的术后结果与术前以损害为导向的患者治疗目标密切相关。然而,目前仍缺乏一种用于测量患者治疗目标与损害程度相关性的临床工具,这阻碍了 TKA 的以患者为导向的适应证选择。

方法

本研究在德国的四家医院招募了计划接受 TKA 的患者。所有患者在术前均接受了 INDICATE 膝关节评分。该评分包含 31 个治疗目标,以及相应的损害,分为七个类别。患者被要求对所有治疗目标和损害进行 3 分制的排序。然后检查治疗目标和损害的出现频率。对目标和损害之间的相关性进行了检验。对不同队列特征(年龄、性别、BMI)与治疗目标的相关性进行了分析。

结果

本研究共纳入了 1298 名患者。7 个治疗目标被归类为超过 90%的患者的“主要目标”(“膝关节疼痛”、“活动范围”、“步行距离”、“整体身体功能”、“爬楼梯”、“生活质量”、“植入物存活率”)。比较不同年龄组,年轻患者(<65 岁)对工作、身体和运动相关的治疗目标有更高的期望,存在显著的相关性(“工作能力”(P≤.001)、“运动活动”(P≤.001)、“性生活”(P≤.001)、“依赖他人帮助”(P=.015)、“预防继发性损害”(P=.03)、“依赖助行器”(P=.005))。更高的 BMI 导致“减重”(P≤.001)、“爬楼梯”(P=.039)、“整体健康状况”(P=.015)和“长时间站立”(P=.007)作为“主要目标”的相关性增加。关于性别的治疗目标差异分析显示,女性比男性选择更多的治疗目标作为“主要目标”。

结论

我们的研究中,超过 90%的患者期望达到的 7 个治疗目标可以被归类为 TKA 的一般治疗目标。人口统计学因素(年龄、性别、BMI)与患者对 TKA 的期望显著相关。我们得出结论,医生在 TKA 前应明确评估患者的需求,以最大限度地提高术后效果。

证据水平

预后 III 级。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00ea/9958169/bf0c2476b4f7/167_2022_7012_Fig1a_HTML.jpg

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