Department of Neurology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325000, China.
Department of Neurology, Ningbo No.2 Hospital, Ningbo, Zhejiang 315000, China.
J Neuroimmunol. 2022 Aug 15;369:577899. doi: 10.1016/j.jneuroim.2022.577899. Epub 2022 Jun 3.
This retrospective study analyzed the clinical characteristics of autoimmune encephalitis (AE) patients to explore the predictors of poor prognosis. According to the modified Rankin scale score at the last follow-up, the functional prognosis of the patients was reflected. And the prognosis of the patients was comprehensively evaluated by the functional prognosis and the relapse of the patients. The results showed that disturbance of consciousness and delayed first-line immunotherapy were independent risk factors for the poor functional prognosis of AE. In addition, patients with psychiatric symptoms, should be alert for relapse.
本回顾性研究分析了自身免疫性脑炎（AE）患者的临床特征，以探讨不良预后的预测因素。根据最后一次随访时的改良 Rankin 量表评分来反映患者的功能预后，并通过患者的功能预后和复发情况对患者的预后进行综合评估。结果表明，意识障碍和一线免疫治疗延迟是 AE 患者功能预后不良的独立危险因素。此外，有精神症状的患者应警惕复发。
