Jensen S L, Hagen K, Shokouh-Amiri M H, Nielsen O V
Dis Colon Rectum. 1987 May;30(5):345-51. doi: 10.1007/BF02555452.
Patients with squamous-cell carcinoma of the anal canal (n = 125) and its margin (n = 76) were divided into five groups: those with an erroneous diagnosis and a correct diagnosis made at first physician visit; those with a history of less than six months, between six and 18 months, and more than 18 months. Patients with canal tumors had an erroneous diagnosis made more frequently than patients with margin tumors. In both groups patients with an erroneous diagnosis had longer histories than patients with a correct diagnosis. Among patients with erroneously diagnosed canal tumor, pain, the feeling of a lump, anal discharge, and pruritus ani occurred less frequently than among correctly diagnosed patients. The prognosis was worse among patients with erroneously diagnosed canal tumors compared with correctly diagnosed patients. Such a difference could not be found among patients with margin tumors. There was a gradual worsening of the prognosis among patients with increasing length of history and canal tumors, in contrast to patients with margin tumors, in whom only a history of more than 18 months was associated with a worse prognosis.
肛管鳞状细胞癌患者（n = 125）及其切缘患者（n = 76）被分为五组：初次就诊时诊断错误和诊断正确的患者；病程小于6个月、6至18个月以及大于18个月的患者。肛管肿瘤患者比切缘肿瘤患者更常出现诊断错误。在两组中，诊断错误的患者病程均比诊断正确的患者长。在诊断错误的肛管肿瘤患者中，疼痛、肿块感、肛门分泌物和肛门瘙痒的发生率低于诊断正确的患者。与诊断正确的患者相比，诊断错误的肛管肿瘤患者预后更差。切缘肿瘤患者之间未发现这种差异。肛管肿瘤患者随着病程延长预后逐渐恶化，而切缘肿瘤患者只有病程超过18个月才与较差的预后相关。
