Edwards A T, Morus L C, Foster M E, Griffith G H
Department of Surgery, Royal Gwent Hospital, Newport.
J R Soc Med. 1991 Jul;84(7):395-7. doi: 10.1177/014107689108400705.
The results of treatment in 22 patients with anal carcinoma are reviewed. The overall results are disappointing with only five (28%) surviving more than 5 years. The commonest form of treatment during the study period was an abdomino-perineal excision of rectum (APER). For patients with tumours less than 2 cm in diameter local excision is an acceptable alternative. The majority (76%) of tumours were diagnosed as common benign conditions by the referring practitioners leading to a delay in initiating definitive treatment. Most tumours (81%) were greater than 2 cm in diameter and therefore unsuitable for local excision. There was a high recurrence rate (76%) amongst the group treated by APER. This along with the poor overall survival is probably due to late presentation.
回顾了22例肛管癌患者的治疗结果。总体结果令人失望，只有5例（28%）存活超过5年。研究期间最常见的治疗方式是腹会阴直肠切除术（APER）。对于直径小于2厘米的肿瘤患者，局部切除是一种可接受的替代方案。大多数（76%）肿瘤被转诊医生诊断为常见良性疾病，导致确定性治疗开始延迟。大多数肿瘤（81%）直径大于2厘米，因此不适合局部切除。接受APER治疗的患者组复发率很高（76%）。这与总体生存率低可能是由于就诊延迟所致。
