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肛管癌:早期诊断的情况

Anal cancer: the case for earlier diagnosis.

作者信息

Edwards A T, Morus L C, Foster M E, Griffith G H

机构信息

Department of Surgery, Royal Gwent Hospital, Newport.

出版信息

J R Soc Med. 1991 Jul;84(7):395-7. doi: 10.1177/014107689108400705.

Abstract

The results of treatment in 22 patients with anal carcinoma are reviewed. The overall results are disappointing with only five (28%) surviving more than 5 years. The commonest form of treatment during the study period was an abdomino-perineal excision of rectum (APER). For patients with tumours less than 2 cm in diameter local excision is an acceptable alternative. The majority (76%) of tumours were diagnosed as common benign conditions by the referring practitioners leading to a delay in initiating definitive treatment. Most tumours (81%) were greater than 2 cm in diameter and therefore unsuitable for local excision. There was a high recurrence rate (76%) amongst the group treated by APER. This along with the poor overall survival is probably due to late presentation.

摘要

回顾了22例肛管癌患者的治疗结果。总体结果令人失望,只有5例(28%)存活超过5年。研究期间最常见的治疗方式是腹会阴直肠切除术(APER)。对于直径小于2厘米的肿瘤患者,局部切除是一种可接受的替代方案。大多数(76%)肿瘤被转诊医生诊断为常见良性疾病,导致确定性治疗开始延迟。大多数肿瘤(81%)直径大于2厘米,因此不适合局部切除。接受APER治疗的患者组复发率很高(76%)。这与总体生存率低可能是由于就诊延迟所致。

本文引用的文献

2
Carcinoma of the anal canal. A clinical and pathologic study of 188 cases.
Cancer. 1984 Jul 1;54(1):114-25. doi: 10.1002/1097-0142(19840701)54:1<114::aid-cncr2820540124>3.0.co;2-p.
7
Changing nature of anal cancer.肛管癌性质的改变
BMJ. 1988 Jul 23;297(6643):239-40. doi: 10.1136/bmj.297.6643.239.

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