Britto E, Borges A M, Swaroop V S, Jagannath P, DeSouza L J
Dis Colon Rectum. 1987 May;30(5):381-5. doi: 10.1007/BF02555459.
A retrospective study of 20 cases of biopsy-proven solitary rectal ulcer syndrome seen at a large oncology hospital which highlight the clinicopathologic features is presented. Thirty five percent of patients were in their sixth decade and there was a male preponderance of 2.3:1. All patients presented with anorectal symptoms. Eighty five percent had normal abdominal findings and seventy five percent had positive findings on rectal examinations. Fifty four percent had a diagnosis of carcinoma of the rectum on barium enema studies. On sigmoidoscopy, a solitary ulcer was found in 80 percent; 50 percent had lesions between 6 and 10 cm from the anal verge, and 40 percent had the lesion on the anterior rectal wall. All patients were treated conservatively and 35 percent were disease free at the end of five years, while 30 percent had persisting symptoms.
本文呈现了一项对一家大型肿瘤医院确诊的20例经活检证实的孤立性直肠溃疡综合征病例的回顾性研究，突出了其临床病理特征。35%的患者年龄在60岁左右，男性占优势，男女比例为2.3:1。所有患者均有肛肠症状。85%的患者腹部检查结果正常，75%的患者直肠检查有阳性发现。54%的患者在钡剂灌肠检查中被诊断为直肠癌。在乙状结肠镜检查中，80%的患者发现有孤立性溃疡；50%的患者病变距肛门边缘6至10厘米，40%的患者病变位于直肠前壁。所有患者均接受保守治疗，五年后35%的患者病情缓解，30%的患者仍有持续症状。
