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孤立性直肠溃疡综合征——临床、内镜及组织学表现谱

Solitary rectal ulcer syndrome--clinical, endoscopic, and histological spectrum.

作者信息

Niv Y, Bat L

出版信息

Am J Gastroenterol. 1986 Jun;81(6):486-91.

PMID:3706271
Abstract

Nineteen patients with solitary rectal ulcer syndrome are presented. The diagnosis was established on sigmoidoscopic and histopathological grounds; the clinical, endoscopic, and histological states were assessed at presentation and on last follow-up. Most of the patients suffered from rectal bleeding, abdominal and anorectal pains, constipation, and straining at defecation. Thirteen patients had macroscopic ulcerations on presentation and six patients did not. These six patients did not develop ulcer during the follow-up period. Four patients entered clinical and endoscopic remission with no histological improvement. Three of them managed conservatively and one underwent suturing of the ulcer and internal anal sphincter dilatation. They remained in remission for a mean follow-up of 1 yr.

摘要

本文报告了19例孤立性直肠溃疡综合征患者。诊断基于乙状结肠镜检查和组织病理学依据;在初诊时和最后一次随访时评估了临床、内镜和组织学状态。大多数患者有直肠出血、腹部和肛门直肠疼痛、便秘以及排便时用力。13例患者初诊时有肉眼可见的溃疡,6例患者没有。这6例患者在随访期间未出现溃疡。4例患者临床和内镜缓解,但组织学无改善。其中3例保守治疗,1例接受了溃疡缝合和肛门内括约肌扩张术。平均随访1年,他们仍处于缓解状态。

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