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摄入中链和长链甘油三酯对胆囊容积及胆囊收缩素和其他肠道肽释放的影响比较。

Comparison of effects of ingested medium- and long-chain triglyceride on gallbladder volume and release of cholecystokinin and other gut peptides.

作者信息

Isaacs P E, Ladas S, Forgacs I C, Dowling R H, Ellam S V, Adrian T E, Bloom S R

出版信息

Dig Dis Sci. 1987 May;32(5):481-6. doi: 10.1007/BF01296030.

DOI:10.1007/BF01296030
PMID:3568934
Abstract

In a double-blind, crossover study of the effect of ingested medium-chain triglyceride (MCT) and long-chain triglyceride (LCT) in six normal subjects, the gallbladder did not contract after ingestion of MCT but instead had significantly increased in volume at 2 hr after the meal. Plasma cholecystokinin (CCK) increased after the MCT meal, but gastrin, motilin, pancreatic polypeptide (PP), and GIP were unaffected. The long-chain triglyceride meal evoked a brisk and sustained gallbladder contraction, higher levels of CCK, and a significant increase in plasma PP and GIP levels.

摘要

在一项针对6名正常受试者的双盲交叉研究中,研究摄入中链甘油三酯(MCT)和长链甘油三酯(LCT)的效果。摄入MCT后,胆囊未收缩,反而在餐后2小时体积显著增加。MCT餐后血浆胆囊收缩素(CCK)升高,但胃泌素、胃动素、胰多肽(PP)和胃抑肽(GIP)未受影响。长链甘油三酯餐引起胆囊快速且持续的收缩、CCK水平升高,以及血浆PP和GIP水平显著增加。

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