Department of Endocrinology and Diabetes, Birmingham Children's Hospital, Birmingham Women's, and Children's NHS Foundation Trust, Birmingham, UK.
College of Medical and Dental Sciences, Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, UK.
Pediatr Diabetes. 2022 Nov;23(7):1045-1056. doi: 10.1111/pedi.13381. Epub 2022 Jul 12.
Compare the clinical and cost-effectiveness of an established face to face (F2F) structured education program to a new remote (VIRTUAL) program teaching dynamic glucose management (DynamicGM) to children and young people with type 1 diabetes (CYPD) using continuous glucose monitoring (CGM). To ascertain the most effective DynamicGM strategies predicting time in range (TIR) (3.9-10.0 mmol/L) and incorporating these into a user-friendly teaching aid.
Effectiveness of the F2F and VIRTUAL programs were ascertained by comparing the mean change (Δ) from baseline to 6 months in HbA1c, TIR and severe hypoglycemia. Delivery cost for the two programs were evaluated. Factors predicting TIR in the combined cohort were determined and incorporated into a user-friendly infographic.
First 50 graduates per group were evaluated. The mean difference in Δ HbA1c, Δ TIR and Δ episodes of severe hypoglycemia between VIRTUAL and F2F groups were 1.16 (p = 0.47), 0.76 (p = 0.78) and -0.06 (p = 0.61) respectively. Delivery cost per 50 CYPD for VIRTUAL and F2F were $5752 and $7020, respectively. The strongest predictors of TIR (n = 100) were short bursts of exercise (10-40 min) to lower hyperglycemia (p < 0.001), using trend arrow adjustment tools (p < 0.001) and adjusting pre-meal bolus timing based on trend arrows (p < 0.01). These strategies were translated into a GAME (Stop highs), SET (Stay in target), MATCH (Prevent lows) mnemonic.
Teaching DynamicGM VIRTUALLY is just as effective as F2F delivery and cost saving. Short bursts of exercise and using CGM trend arrows to adjust insulin dose and timing improves TIR.
比较面对面(F2F)结构化教育计划和新的远程(虚拟)计划在使用连续血糖监测(CGM)教授 1 型糖尿病儿童和青少年动态血糖管理(DynamicGM)方面的临床和成本效益,前者使用传统方法,后者使用新技术。确定最有效的预测时间在范围内(TIR)(3.9-10.0mmol/L)的 DynamicGM 策略,并将这些策略纳入用户友好的教学工具。
通过比较基线至 6 个月时糖化血红蛋白(HbA1c)、TIR 和严重低血糖的平均变化(Δ),确定 F2F 和 VIRTUAL 计划的有效性。评估两个计划的交付成本。确定联合队列中预测 TIR 的因素,并将其纳入用户友好的信息图中。
每组评估前 50 名毕业生。VIRTUAL 组和 F2F 组在ΔHbA1c、ΔTIR 和Δ严重低血糖事件方面的平均差异分别为 1.16(p=0.47)、0.76(p=0.78)和-0.06(p=0.61)。VIRTUAL 和 F2F 每 50 例 CYPD 的交付成本分别为 5752 美元和 7020 美元。TIR(n=100)的最强预测因素是降低高血糖的短时间爆发性运动(10-40 分钟)(p<0.001)、使用趋势箭头调整工具(p<0.001)和根据趋势箭头调整餐前胰岛素剂量(p<0.01)。这些策略被转化为一个游戏(停止高血糖)、设置(保持在目标范围内)、匹配(预防低血糖)的记忆法。
远程教学 DynamicGM 与面对面教学一样有效,且具有成本效益。短时间爆发性运动和使用 CGM 趋势箭头来调整胰岛素剂量和时间可以提高 TIR。