Department of Endocrinology and Diabetes, Birmingham Children's Hospital, Birmingham Women's and Children's NHS Foundation Trust, Birmingham, UK.
Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
Pediatr Diabetes. 2021 Mar;22(2):249-260. doi: 10.1111/pedi.13155. Epub 2021 Jan 15.
Create and evaluate the effectiveness of a structured education program in children and young people (CYP) with type 1 diabetes using continuous glucose monitoring (CGM).
Step 1: CGM devices were evaluated for predetermined criteria using a composite score. Step 2: The education program was developed following review of international structured education guidance, dynamic glucose management (DynamicGM) literature, award-winning diabetes educators' websites, and CGM user feedback. Step 3: Program effectiveness was assessed at six months by change in time below range (TBR) (<3.9mmol/L), time in range (TIR) (3.9-10.0mmol/L), time above range level 2 (TAR2) (>13.9mmol/L), severe hypoglycemia and HbA1c using a paired T-test. A DynamicGM score was developed to assess proactive glucose management. Factors predicting TBR and TIR were assessed using regression analysis.
Dexcom G6 was chosen for integrated CGM (iCGM) status and highest composite score (29/30). Progressive DynamicGM strategies were taught through five sessions delivered over two months. Fifty CYP (23 male) with a mean (±SD) age and diabetes duration of 10.2 (±4.8) and 5.2 (±3.7) years respectively, who completed the education program were prospectively evaluated. Evaluation at six months showed a significant reduction in TBR (10.4% to 2.1%, p<.001), TAR2 (14.1% to 7.3%, p<.001), HbA1c [7.4 to 7.1% (57.7 to 53.8 mmol/mol), p<.001] and severe hypoglycemic episodes (10 to 1, p<.05); TIR increased (47.4% to 57.0%, p<.001). Number of Dexcom followers (p<.05) predicted reduction in TBR and DynamicGM score (p<.001) predicted increased TIR.
Teaching DynamicGM strategies successfully improves TIR and reduces hypoglycemia.
使用连续血糖监测(CGM)为 1 型糖尿病的儿童和青少年(CYP)创建并评估结构化教育计划的效果。
第 1 步:使用综合评分评估 CGM 设备是否符合预定标准。第 2 步:根据国际结构化教育指南、动态血糖管理(DynamicGM)文献、获奖糖尿病教育者的网站和 CGM 用户反馈回顾,开发教育计划。第 3 步:在六个月时通过时间低于范围(TBR)(<3.9mmol/L)、时间在范围内(TIR)(3.9-10.0mmol/L)、范围 2 以上时间(TAR2)(>13.9mmol/L)、严重低血糖和糖化血红蛋白(HbA1c)的变化来评估计划效果,使用配对 T 检验。开发了一个动态血糖管理评分来评估主动血糖管理。使用回归分析评估预测 TBR 和 TIR 的因素。
Dexcom G6 因其集成 CGM(iCGM)状态和最高综合评分(29/30)而被选为 CGM。通过五个课程在两个月内教授逐步的动态血糖管理策略。50 名 CYP(23 名男性)完成了教育计划,他们的平均(±SD)年龄和糖尿病病程分别为 10.2(±4.8)和 5.2(±3.7)年。六个月的评估显示 TBR(从 10.4%降至 2.1%,p<.001)、TAR2(从 14.1%降至 7.3%,p<.001)、HbA1c [从 7.4 降至 7.1%(57.7 至 53.8mmol/mol),p<.001]和严重低血糖发作(从 10 降至 1,p<.05)显著减少;TIR 增加(从 47.4%增至 57.0%,p<.001)。 Dexcom 关注者的数量(p<.05)预测 TBR 减少,动态血糖管理评分(p<.001)预测 TIR 增加。
教授动态血糖管理策略可成功提高 TIR 并减少低血糖。