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儿童耳廓利什曼病经病灶内注射两性霉素 B 成功治愈。

Auricular leishmaniasis in a child successfully treated with intralesional amphotericin B.

机构信息

Dermatology Unit and Genodermatosis Unit, Genetics and Rare Diseases Research Division, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.

Unit of Infectious Diseases, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.

出版信息

Pediatr Dermatol. 2022 Sep;39(5):832-833. doi: 10.1111/pde.15046. Epub 2022 Jun 11.

DOI:10.1111/pde.15046
PMID:35689474
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9796609/
Abstract

Cutaneous leishmaniasis (CL) is the most frequent form of leishmaniasis. The auricle is an extremely rare site for CL in the Old World. Auricular CL may be mistaken for other entities, such as relapsing polychondritis (RP). Here we report a pediatric case of Old World auricular CL mimicking RP in a child successfully treated with intralesional liposomal amphotericin B.

摘要

皮肤利什曼病（CL）是最常见的利什曼病形式。在旧世界中，耳廓是 CL 极为罕见的部位。耳廓 CL 可能被误诊为其他实体疾病，如复发性多软骨炎（RP）。我们在此报告一例小儿病例，其旧世界耳廓 CL 模仿 RP，采用腔内注射两性霉素 B 脂质体成功治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b94e/9796609/4499825d52aa/PDE-39-832-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b94e/9796609/4499825d52aa/PDE-39-832-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b94e/9796609/4499825d52aa/PDE-39-832-g001.jpg

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本文引用的文献

1
Cutaneous leishmaniasis: A great imitator.皮肤利什曼病：一个伟大的模仿者。
Clin Dermatol. 2020 Mar-Apr;38(2):140-151. doi: 10.1016/j.clindermatol.2019.10.008. Epub 2019 Oct 24.
2
Comparison of Efficacy of Two Different Concentrations of Intralesional Amphotericin B in the Treatment of Cutaneous Leishmaniasis; A Randomized Controlled Trial.两种不同浓度的两性霉素B皮损内注射治疗皮肤利什曼病的疗效比较：一项随机对照试验
Indian Dermatol Online J. 2019 Nov 1;10(6):627-631. doi: 10.4103/idoj.IDOJ_470_18. eCollection 2019 Nov-Dec.
3
Leishmania tropica in children: a retrospective study.
儿童内脏利什曼病：一项回顾性研究。
J Am Acad Dermatol. 2014 Aug;71(2):271-7. doi: 10.1016/j.jaad.2013.12.047. Epub 2014 Apr 26.
4
Auricular enlargement: an atypical presentation of old world cutaneous leishmaniasis.耳部肿大：旧世界皮肤利什曼病的一种非典型表现。
Indian J Dermatol. 2011 Jul;56(4):428-9. doi: 10.4103/0019-5154.84750.
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Cutaneous leishmaniasis: an atypical case.皮肤利什曼病：一个非典型病例。
Int J Dermatol. 2005 Jan;44(1):38-40. doi: 10.1111/j.1365-4632.2004.02190.x.