Augustin N, Wagner P K, Rothmund M
Dtsch Med Wochenschr. 1987 Apr 17;112(16):636-41. doi: 10.1055/s-2008-1068111.
From 1965 to 1985, 412 patients were operated on for primary hyperparathyroidism (pHPT). Of these, 35 (8.7%) were without specific symptoms and findings. The follow-up investigations after six months to 14 years (median: 31 months) revealed a normalization of the preoperative pathological parameters of alkaline phosphatase, uric acid, creatinine and hypertension in the majority of patients apart from the improvement of their general condition. All patients were normocalcemic. According to these results, the indication for early surgical therapy of the asymptomatic pHPT is to be advocated in order to avoid long-term complications.
1965年至1985年期间，412例患者因原发性甲状旁腺功能亢进症（pHPT）接受了手术治疗。其中，35例（8.7%）无特异性症状和体征。六个月至十四年（中位数：31个月）的随访调查显示，除一般状况改善外，大多数患者术前碱性磷酸酶、尿酸、肌酐和高血压等病理参数恢复正常。所有患者血钙正常。根据这些结果，主张对无症状pHPT进行早期手术治疗，以避免长期并发症。
