Bristol Trials Centre, University of Bristol, Bristol, UK.
Bristol Heart Institute, University of Bristol, Bristol, UK.
BMC Res Notes. 2022 Jun 11;15(1):202. doi: 10.1186/s13104-022-06088-y.
To narratively describe the challenges and solutions required in delivering a non-commercial study of children undergoing cardiac surgery using a novel subcutaneous hormone collection device.
The challenges faced by the research team are divided into those of conducting healthcare research in children and those specific to this study. Many of the issues of conducting healthcare research in children can and have been overcome by structural and institutional culture change-normalising and embedding research as part of good clinical care. The issues specific to insertion and maintenance of the novel collection device can be overcome by education and support of the clinical teams. The increased incentives and resources of commercial research may have overcome many of these.
叙述在使用新型皮下激素采集装置对接受心脏手术的儿童进行非商业研究时所遇到的挑战和需要解决的问题。
研究团队面临的挑战分为儿童保健研究相关挑战和本研究特有的挑战。通过结构和机构文化变革——将研究作为良好临床护理的一部分进行规范化和嵌入，可以解决许多在儿童中开展医疗保健研究的问题。新型采集装置的插入和维护问题可以通过对临床团队的教育和支持来解决。商业研究的更多激励措施和资源可能已经解决了其中的许多问题。
