Division of Endocrinology and Metabolism, Department of Medicine, University of Virginia School of Medicine, Charlottesville, VA 22908, USA.
Endocrine Society, Washington, DC 20036, USA.
J Clin Endocrinol Metab. 2022 Jul 14;107(8):2129-2138. doi: 10.1210/clinem/dgac290.
In an effort to enhance the trustworthiness of its clinical practice guidelines, the Endocrine Society has recently adopted new policies and more rigorous methodologies for its guideline program. In this Clinical Practice Guideline Communication, we describe these recent enhancements-many of which reflect greater adherence to the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) approach to guideline development-in addition to the rationale for such changes. Improvements to the Society's guideline development practices include, but are not limited to, enhanced inclusion of nonendocrinologist experts, including patient representatives, on guideline development panels; implementation of a more rigorous conflict/duality of interest policy; a requirement that all formal recommendations must be demonstrably underpinned by systematic evidence review; the explicit use of GRADE Evidence-to-Decision frameworks; greater use and explanation of standardized guideline language; and a more intentional approach to guideline updating. Lastly, we describe some of the experiential differences our guideline readers are most likely to notice.
为了提高临床实践指南的可信度，内分泌学会最近为其指南计划采用了新政策和更严格的方法。在本临床实践指南交流中，我们描述了这些最近的增强措施——其中许多措施反映了对指南制定的推荐分级评估、制定与评价（GRADE）方法的更高遵循度——以及此类变化的基本原理。学会指南制定实践的改进包括但不限于：更多地包括非内分泌专家，包括患者代表，参与指南制定小组；实施更严格的冲突/利益冲突政策；要求所有正式建议必须有系统的证据审查作为依据；明确使用 GRADE 证据决策框架；更多地使用和解释标准化指南语言；以及更有意识地进行指南更新。最后，我们描述了我们的指南读者最有可能注意到的一些经验差异。
