Department of Obstetrics and Gynaecology, Kathmandu Medical College and Teaching Hospital, Sinamangal, Kathmandu, Nepal.
JNMA J Nepal Med Assoc. 2022 Jun 1;60(250):577-580. doi: 10.31729/jnma.7333.
Uterine leiomyoma is the most common benign tumour of the female reproductive tract originating from the uterine smooth muscle causing morbidity and impairing their quality of life. It is common among women in the age group 30 to 50 years of age. Women are usually asymptomatic or may present with various symptoms such as abnormal uterine bleeding, pelvic pain, dysmenorrhea, and change in bowel and bladder habits due to pressure symptoms. It is one of the leading causes of hysterectomy. Women with uterine leiomyoma can be managed medically and surgically. Gonadotropin-releasing hormone analogue is one of the modalities used preoperatively to reduce the size of large uterine fibroid. We present the case report of a 36-year-old nulligravida who underwent total abdominal hysterectomy with bilateral salpingectomy for large uterine leiomyoma weighing 5.61 kg without compression symptoms. She received a gonadotropin-releasing hormone agonist (injection leuprolide) preoperatively for reduction of the size of uterine myoma.
case reports; gonadotropin-releasing hormone; hysterectomy; leiomyoma.
子宫肌瘤是女性生殖系统最常见的良性肿瘤,起源于子宫平滑肌,导致发病率增加,并降低其生活质量。它常见于 30 至 50 岁的妇女。妇女通常无症状,或可能出现各种症状,如异常子宫出血、盆腔疼痛、痛经以及由于压迫症状导致的肠道和膀胱习惯改变。它是子宫切除术的主要原因之一。子宫肌瘤患者可以通过医学和手术进行治疗。促性腺激素释放激素类似物是术前用于缩小大型子宫肌瘤的一种方法。我们报告了一例 36 岁的初产妇,她因巨大子宫肌瘤(重达 5.61 公斤)而接受了全子宫切除术和双侧输卵管切除术,但无压迫症状。她在术前接受了促性腺激素释放激素激动剂(注射用亮丙瑞林)治疗,以缩小子宫肌瘤的大小。
病例报告;促性腺激素释放激素;子宫切除术;肌瘤。