Scheer M L J, Slebos D J, Bogchelman D H, Timens W
Universitair Medisch Centrum Groningen, afd. Longziekten, Postbus 30.001, 9700 RB Groningen.
Ned Tijdschr Geneeskd. 2008 Sep 13;152(37):2027-31.
A 49-year-old woman, who had undergone a hysterectomy 17 years previously, was referred with thoracic pain located on the right side that had been present for several weeks. Thoracic imaging showed multiple pulmonary lesions on both sides. Histological investigation of a biopsy from one of these lesions revealed a benign metastatic leiomyoma. The patient was treated with gonadotropin-releasing hormone (GnRH) analogue. The lesions showed regression and the symptoms disappeared. Benign metastatic leiomyoma is a rare benign clinical entity in women of fertile age who have had a surgical intervention on the uterus because of uterus myomatosus. The therapeutic options are surgical resection, removal of the hormonal stimulus by administering progesterone or GnRH-analogues or bilateral ovariectomy.
一名49岁女性，17年前接受过子宫切除术，因右侧胸痛数周前来就诊。胸部影像学检查显示双侧有多个肺部病变。对其中一个病变进行活检的组织学检查显示为良性转移性平滑肌瘤。患者接受了促性腺激素释放激素（GnRH）类似物治疗。病变有所消退，症状消失。良性转移性平滑肌瘤是育龄期女性中一种罕见的良性临床病症，这些女性因子宫肌瘤而接受了子宫手术干预。治疗选择包括手术切除、通过给予孕激素或GnRH类似物去除激素刺激或双侧卵巢切除术。
