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检查头颈部癌症患者停止随访护理的风险因素。

Examination of risk factors for discontinuation of follow-up care in patients with head and neck cancer.

机构信息

Department of Behavioral Sciences & Social Medicine, College of Medicine, Florida State University, Tallahassee, Florida, USA.

Florida Blue Center for Rural Health Research & Policy, College of Medicine, Florida State University, Tallahassee, Florida, USA.

出版信息

Cancer Med. 2023 Jan;12(1):631-639. doi: 10.1002/cam4.4944. Epub 2022 Jun 12.

Abstract

BACKGROUND

Little research has examined discontinuation of follow-up care in patients with head and neck cancer. This exploratory study sought to examine key demographic, disease, and behavioral factors as possible correlates of discontinuation (N = 512).

METHODS

Cross-sectional study examined correlates of discontinuation of follow-up care within 1 year. The primary outcome was defined as a disease-free survivor not returning to cancer clinic for two consecutive follow-up appointments within the first year of care and not reentering oncologic care at any point thereafter. Demographic, disease, and behavioral factors were examined using multivariable logistic regression.

RESULTS

One hundred twenty-six (24.6%) patients discontinued by 12-month follow-up. Being unmarried (OR = 1.28, 95% CI = 1.01-1.63, p = 0.041) and having elevated depressive symptomatology (OR = 1.04, 95% CI = 1.01-1.07, p = 0.034) were significantly associated with discontinuation. Receipt of a single (vs. multimodal) treatment approached significance (OR = 1.71, 95% CI = 0.96-3.07, p = 0.071).

CONCLUSION

Approximately one quarter of patients disengaged from important follow-up care within 1 year. Lack of social support, depressive symptomatology, and single treatment modality may be important correlates of discontinuation of care in patients with head and neck cancer. Additional studies of this outcome are needed. Improved understanding of correlates associated with discontinuation could facilitate the identification of at-risk patients and further development of interventions to keep patients engaged at a crucial time in the survivorship care trajectory.

摘要

背景

针对头颈部癌症患者停止随访护理的研究较少。本探索性研究旨在检查关键的人口统计学、疾病和行为因素,这些因素可能与停止随访护理相关(N=512)。

方法

本横断面研究检查了 1 年内停止随访护理的相关因素。主要结局定义为无疾病幸存者在护理的第一年中连续两次错过癌症门诊随访预约,且此后未重新进入肿瘤学护理。使用多变量逻辑回归分析人口统计学、疾病和行为因素。

结果

126 名(24.6%)患者在 12 个月随访时停止随访。未婚(比值比[OR] = 1.28,95%置信区间[CI] = 1.01-1.63,p=0.041)和存在较高的抑郁症状(OR=1.04,95%CI=1.01-1.07,p=0.034)与停止随访显著相关。接受单一(而非多模式)治疗的患者(OR=1.71,95%CI=0.96-3.07,p=0.071)接近显著。

结论

大约四分之一的患者在 1 年内停止了重要的随访护理。缺乏社会支持、抑郁症状和单一治疗方式可能是头颈部癌症患者停止护理的重要相关因素。需要进一步研究这一结果。更好地了解与停止治疗相关的因素可以帮助识别高危患者,并进一步开发干预措施,在生存护理轨迹的关键时期保持患者的参与。

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