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Management of severe asthma: from stepwise approach to therapy to treatable traits?

作者信息

Wang Gang, McDonald Vanessa M, Gibson Peter G

机构信息

Department of Respiratory and Critical Care Medicine, Clinical Research Center for Respiratory Disease, West China Hospital, Sichuan University, Chengdu 610041, China.

Department of Respiratory and Sleep Medicine, John Hunter Hospital, Hunter Medical Research Institute, Newcastle 2305, Australia.

出版信息

Precis Clin Med. 2021 Dec 3;4(4):293-296. doi: 10.1093/pcmedi/pbab028. eCollection 2021 Dec.

DOI:10.1093/pcmedi/pbab028
PMID:35692859
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8982611/
Abstract
摘要

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引用本文的文献

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Workup of difficult-to-treat asthma: implications from treatable traits.难治性哮喘的检查：可治疗特征的影响
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Reduced Skeletal Muscle Mass Is Associated with an Increased Risk of Asthma Control and Exacerbation.骨骼肌质量降低与哮喘控制不佳及病情加重风险增加相关。
J Clin Med. 2022 Dec 6;11(23):7241. doi: 10.3390/jcm11237241.

本文引用的文献

1
Treatable Traits in Elderly Asthmatics from the Australasian Severe Asthma Network: A Prospective Cohort Study.澳大利亚严重哮喘网络老年哮喘可治疗特征：一项前瞻性队列研究。
J Allergy Clin Immunol Pract. 2021 Jul;9(7):2770-2782. doi: 10.1016/j.jaip.2021.03.042. Epub 2021 Apr 5.
2
Multidimensional Assessment of Asthma Identifies Clinically Relevant Phenotype Overlap: A Cross-Sectional Study.哮喘的多维评估可识别具有临床相关性的表型重叠：一项横断面研究。
J Allergy Clin Immunol Pract. 2021 Jan;9(1):349-362.e18. doi: 10.1016/j.jaip.2020.07.048. Epub 2020 Aug 11.
3
Targeting treatable traits in severe asthma: a randomised controlled trial.针对重度哮喘可治疗特征的随机对照试验。
Eur Respir J. 2020 Mar 5;55(3). doi: 10.1183/13993003.01509-2019. Print 2020 Mar.
4
Treatable traits: a new paradigm for 21st century management of chronic airway diseases: Treatable Traits Down Under International Workshop report.可治疗特征：21 世纪慢性气道疾病管理的新模式：可治疗特征在澳大利亚国际研讨会报告
Eur Respir J. 2019 May 9;53(5). doi: 10.1183/13993003.02058-2018. Print 2019 May.
5
Treatable traits in the European U-BIOPRED adult asthma cohorts.欧洲U-BIOPRED成人哮喘队列中的可治疗特征。
Allergy. 2019 Feb;74(2):406-411. doi: 10.1111/all.13629. Epub 2018 Nov 12.
6
Treatable traits can be identified in a severe asthma registry and predict future exacerbations.可在严重哮喘登记处中识别可治疗的特征，并预测未来的加重。
Respirology. 2019 Jan;24(1):37-47. doi: 10.1111/resp.13389. Epub 2018 Sep 19.
7
After asthma: redefining airways diseases.哮喘之后：重新定义气道疾病。
Lancet. 2018 Jan 27;391(10118):350-400. doi: 10.1016/S0140-6736(17)30879-6. Epub 2017 Sep 11.
8
Mepolizumab and exacerbations of refractory eosinophilic asthma.美泊利珠单抗与难治性嗜酸性粒细胞性哮喘的病情加重
N Engl J Med. 2009 Mar 5;360(10):973-84. doi: 10.1056/NEJMoa0808991.
9
A study to evaluate safety and efficacy of mepolizumab in patients with moderate persistent asthma.一项评估美泊利单抗治疗中度持续性哮喘患者的安全性和有效性的研究。
Am J Respir Crit Care Med. 2007 Dec 1;176(11):1062-71. doi: 10.1164/rccm.200701-085OC. Epub 2007 Sep 13.