Uno H, Sawai H, Fukuda Y
Exp Neurol. 1987 May;96(2):462-8. doi: 10.1016/0014-4886(87)90063-x.
Single cell responses to electrical stimuli applied to the optic chiasm and to the lateral geniculate nucleus were studied in expanded projection to the ipsilateral superior colliculus of neonatally enucleated and congenitally monocular rats. In both types of rats latencies to the afferent volleys were longer, and the latency correlation between the optic chiasm and the lateral geniculate responses was lower in the ipsilateral than in the contralateral superior colliculus cells. This was interpreted to suggest abnormal convergence of retinal axons with different conduction velocities in the ipsilateral retinocollicular projection. The deviation of ipsilateral superior colliculus cells from the high-latency correlation of the contralateral cells was more marked in congenitally monocular than in neonatally enucleated rats.
在新生期摘除眼球和先天性单眼大鼠的同侧上丘扩展投射中，研究了对视交叉和外侧膝状体施加电刺激的单细胞反应。在这两种类型的大鼠中，传入冲动的潜伏期更长，并且同侧上丘细胞中，视交叉和外侧膝状体反应之间的潜伏期相关性低于对侧上丘细胞。这被解释为提示同侧视网膜 - 上丘投射中具有不同传导速度的视网膜轴突存在异常汇聚。先天性单眼大鼠同侧上丘细胞与对侧细胞高潜伏期相关性的偏差比新生期摘除眼球的大鼠更明显。
