Habgood M D, Hopkins W G
Exp Neurol. 1987 May;96(2):474-8. doi: 10.1016/0014-4886(87)90065-3.
An electron microscopic investigation of neuromuscular synapses of the tensor fasciae latae muscle in juvenile mice was carried out to determine the relationship between the presynaptic (nerve terminal) and postsynaptic (end-plate plaque) elements during the major phase of postnatal growth. In the first month of life growth of the synapse was accompanied by a decrease in the size of pre- and postsynaptic elements in cross section. A decrease in the fraction of the width of end-plate plaque opposed by nerve terminal was also observed to age 2 months, and in older animal some end-plate plaques were completely unopposed by nerve terminal. This implies that end plates grow at a faster rate than nerve terminals and suggests that the availability of uninnervated, differentiated end plate permits or promotes nerve terminal growth.
对幼年小鼠阔筋膜张肌神经肌肉突触进行了电子显微镜研究，以确定出生后生长的主要阶段突触前（神经末梢）和突触后（终板斑）成分之间的关系。在出生后的第一个月，突触的生长伴随着突触前和突触后成分横截面积的减小。到2个月大时，还观察到神经末梢相对的终板斑宽度比例下降，而在年长动物中，一些终板斑完全没有神经末梢相对。这意味着终板的生长速度比神经末梢快，并表明未受神经支配的、已分化终板的存在允许或促进了神经末梢的生长。
