Radiology and Nuclear Medicine, Utrecht University and University Medical Center, Utrecht, Netherlands.
Expert Rev Med Devices. 2022 May;19(5):393-403. doi: 10.1080/17434440.2022.2088355. Epub 2022 Jun 14.
Handheld gamma cameras and gamma probes have been successfully implemented for enabling nuclear image or radio-guidance in minimally-invasive procedures. There is an opportunity for large field-of-view interventional planar scintigraphy and SPECT imaging to complement these small field-of-view devices for two reasons. First, a large field-of-view camera enables imaging of relatively larger organs and activity accumulations that are not close to the patient's skin. And second, more precise corrections can be implemented in the SPECT reconstruction algorithm, improving its quality.
This review article discusses the progress that has been made in the field of large field-of-view interventional planar scintigraphy and SPECT imaging. First, an overview of planar scintigraphy and SPECT is provided. Second, an exploration is given of the potential applications where large field-of-view interventional planar scintigraphy and SPECT imaging may be employed. And third, the requirements for scanner hardware are discussed and an overview of the possible system configurations is provided.
We believe that there is an opportunity for large field-of-view interventional planar scintigraphy and SPECT imaging to assist clinical workflows. A major effort is now required to evaluate the prototype systems in clinical studies so that valuable practical experience can be obtained.
手持式伽马相机和伽马探头已成功应用于微创程序中的核医学图像或放射性引导。大视野介入平面闪烁成像和 SPECT 成像是有机会补充这些小视野设备的，原因有二。首先，大视野相机能够对相对较大的器官和远离患者皮肤的放射性积聚进行成像。其次，可以在 SPECT 重建算法中实施更精确的校正，从而提高其质量。
本文讨论了大视野介入平面闪烁成像和 SPECT 成像领域的进展。首先，概述了平面闪烁成像和 SPECT。其次，探讨了大视野介入平面闪烁成像和 SPECT 成像可能应用的潜在领域。第三，讨论了扫描仪硬件的要求，并提供了可能的系统配置概述。
我们认为，大视野介入平面闪烁成像和 SPECT 成像有机会辅助临床工作流程。现在需要进行大量的工作来评估临床研究中的原型系统，以便获得有价值的实际经验。
